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The use of antiretroviral medicines (ART) after potential exposure to HIV to prevent infection is called post-exposure prophylaxis (PEP). It should be used only in emergencies, and within 72 hours after a possible exposure. It has to be taken ones or twice a day for 28 days. PEP is shown to be useful but not 100 %, so it is always better to engage in safe sex. The antiviral drugs used are Tenofovir, Emtricitabine, Raltegravir, and Dolutegravir. The common side effects of PEP drugs are nausea, headaches, fatigue, insomnia, and liver problems. The other serious problem with this treatment is if the antiviral medicines do not work and you get infected, the virus might be resistant to some HIV drugs.