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What is the role of tau protein in Alzheimer's disease?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am a 50-year-old female. I have recently been diagnosed with Alzheimer's disease and have been researching the role of tau protein in this condition. I am eager to understand more about how tau protein affects neurons and contributes to the progression of Alzheimer's symptoms. Could you please explain in simpler terms what tau protein is and how its accumulation impacts the brain? I am also curious to know if there are any treatment options for targeting tau protein that I should consider exploring.

Kindly help.

Hello,

Welcome to icliniq.com.

I can understand your concern.

Tau protein is like a support structure for brain cells, helping them maintain their shape and function. In Alzheimer's, tau proteins can become abnormal and clump together inside neurons, causing them to malfunction and eventually die. This leads to memory loss and other symptoms. Some research focuses on treatments that aim to clear or prevent the buildup of these abnormal tau proteins, which could potentially slow down the progression of Alzheimer's. These treatments are still being studied. You should try to follow a lifestyle that helps you to prevent cognitive impairment like:

  1. You should do exercises daily for 30 to 45 minutes like at least going for a walk.
  2. You should do meditation for 20 minutes daily, just sit in one place in a comfortable position, and try to concentrate on your normal breathing, do not stop or force yourself to stop your thoughts, just let it be.
  3. You should eat healthy home-cooked foods, and avoid junk food.
  4. You must drink enough water.
  5. You should spend quality time with friends and family daily or do video calls if you are living away from your family.
  6. You should spend time on creative hobbies like reading good books, writing journals, painting, drawing, and learning new skills or language or musical instruments.
  7. You should take seven to eight hours of sleep daily.
  8. You must avoid tobacco alcohol or any substance abuse.

There are some medications like Donepezil (Aricept), and Rivastigmine (Exelon) which can help in delaying the progression of your dementia. Consult your specialist doctor, discuss with them, and take the medicines with their consent.

I hope that you get your answer.

Please, let me know if you want some more help.

Thank you.

Medically reviewed byiCliniq medical review team

Published At July 7, 2024
Reviewed AtJuly 7, 2024

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