The medicines used to treat the symptoms of clinical depression are called antidepressants. They are also used to treat generalized anxiety disorder (GAD), obsessive-compulsive disorder (OCD), and sometimes for post-traumatic stress disorder. Some of the antidepressants commonly used are Fluoxetine, Imipramine, Bupropion, and Sertraline.

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I am tapering off my antidepressant medication, and my depression has gotten very severe. What should I do?

Query: Hi doctor, I am currently in the middle of a cross taper off of Gabapentin (previously at 600 milligrams, now off of it) and Lamictal (previously at 400 milligrams and now at 100 milligrams). In comparison, I continued taking 300 milligrams of Wellbutrin, which I titrated up to several days after st...  Read Full »

Dr. Vandana Patidar

Answer: Hi, Welcome to Here are my opinions based on your description, which may or may not be right because to diagnose an Illness, you need details of symptoms. So, in my opinion, if Lamictal or Lamotrigine and Quetiapine helped you and now tapering, it is causing a problem. But, on the othe...  Read Full »

I suffer from depression, burnouts, and meltdowns because of autism spectrum disorder. Are antidepressants helpful in treating it?

Query: Hello doctor,I want to contact you to inquire about anti-depressive treatment in persons affected by autism spectrum syndrome (ASS), for instance, Asperger syndrome or high functioning autism in adults.Is there any antidepressant effective for ASS, especially molecules like Tranylcypromine parnate (...  Read Full »

Dr. Vandana Patidar

Answer: Hello, Welcome to Antidepressants usually do not seem to affect core symptoms of autistic spectrum disorder. I did not see any clinical patient with autistic spectrum disorder with Tranylcypromine. We do not usually suggest an antidepressant medicine to an autistic spectrum patient in...  Read Full »

Can having Fluoxetine with Venlafaxine lift depression?

Query: Hello doctor, Will having 20 mg Fluoxetine added to my existing 375 mg of Venlafaxine help to lift my depression? I had recurring depression since 17 and have been on Venlafaxine for 12 years.  Read Full »

Dr. Vandana Patidar

Answer: Hello, Welcome to Venlafaxine is a very good anti-depressant. It has given you excellent results for 12 years but if the problem is increasing then there might be some issues like hormonal imbalance, psychosocial problems, substance abuse, etc. We need details on that. At times, addre...  Read Full »

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