Autoimmune Pathology

Autoimmune disease is a condition where the body's immune system attacks the healthy cells in the body. The pathogenesis of autoimmune diseases are genes, the immune system, and the environment where the affected person lives. The immune system gets dysregulated and causes pathological changes in the body. Common autoimmune disorders affecting the body are Addison's disease, Graves' disease, Hashimoto's thyroiditis, multiple sclerosis, diabetes type 1, and pernicious anemia.

Recently Answered Questions Recently Answered Questions

All the answers published in this website are written by verified medical doctors, therapists and health experts. The Content has been moderated by iCliniq medical review team before publication. Post your medical clarifications on iCliniq by choosing the right specialty and get them answered. Your medical queries will be answered 24/7 by top doctors from iCliniq.

What does borderline positive c-ANCA levels indicate?

Query: Hello doctor, My c-ANCA levels are 5.6 U/ml (borderline positive). I have hypertension and proteinuria (3g), high serum creatinine (2.4) and UTI. My other autoimmune tests and serum electrophoresis results are negative. What should I do and what is the general prognosis?  Read Full »


Dr. Anshul Varshney

Answer: Hi, Welcome to icliniq.com. Based on your query, my opinion is as follows: C-ANCA (Antineutrophil cytoplasmic antibodies) positivity indicates Wegener's Granulomatosis. In this condition, there is involvement of upper and lower respiratory tract and kidneys. Most common diagnosis, while kidneys a...  Read Full »

Is it fine to take Prednisone and Azathioprine for autoimmune hepatitis?

Query: Hi doctor, I have been itching throughout my body, especially after eating, for about two years. I noticed fatigue and shortness of breath about 18 months ago. I stopped smoking before seven years. I stopped drinking before a year as my upper abdominal area started paining after drinking. Before fi...  Read Full »


Dr. Sadaf Mustafa

Answer: Hi, Welcome to icliniq.com. There are a few important facts I would want you to consider. We have to rule out other forms of hepatitis like viral hepatitis, amyloid or iron deposition, NASH (nonalcoholic steatohepatitis) and alcoholic liver disease. All three markers are non-specific;...  Read Full »

What can cause diffuse cerebral atrophy?

Query: Hi doctor, My sister is a 45 year old female. She had two episodes of unconsciousness. Her BP usually is normal at 80/58 mmHg and pulse 76 to 80 beats per minute.  We got an MRI done which showed diffuse cerebral atrophy with chronic ischaemic changes. MRA normal with no flow limiting significant ...  Read Full »


Dr. Ashok Kumar

Answer: Hi, Welcome to icliniq.com. From the attached MRI report (attachment removed to protect patient identity) it seems that vascular pathology is the primary cause for the MRI changes in brain. The current pathology indicates that she had poor blood supply for last few years. The reason may b...  Read Full »

What does the unknown neurological condition I am diagnosed with mean?

Query: Hello doctor, I am a 60 year old female, who is 5.4 feet, and I weighs 157 lbs. I am looking for a name for my condition. The only medication I take is Imipramine hydrochloride 40 mg tablets each day. I have been told that I have a neurological condition, but the symptoms do not follow any diagnosis...  Read Full »


Dr. Jeremy David O' Kennedy

Answer: Hi, Welcome to icliniq.com. Sorry to hear about your prolonged symptoms, I can understand your frustration.Your complaints mostly encompass two of the most complex systems of medicine, that is neurology and immunology. There is a lot we know, but that probably makes up just 20 % of what is yet to be...  Read Full »

Why are there tremors, speech problems and memory disturbances?

Query: Hello doctor, For the past few years, I have been having the following symptoms: 1) Tremors. 2) Pain near the spinal cord. 3) Head stiffness. 4) Getting stuck when thinking or solving things. Please advise.  Read Full »


Dr. Jaydeep Tripathy

Answer: Hi, Welcome to icliniq.com. I would like to know the following details: 1) May I know your age? 2) Do you have any history of hypertension or diabetes? 3) Do you have any history of previous tuberculosis? I will suggest an immediate MRI (magnetic resonance imaging) of the brain to rule out deg...  Read Full »

Can I rely on fourth-generation HIV test result after six months of exposure?

Query: Hello doctor, How accurate is HIV test after six months? What are the things that affect or delay the HIV test? I am taking Ashwaghanda, does it delay my test? When should I test if I have an autoimmune disease?  Read Full »


Dr. Purushottam Sah

Answer: Hello, Welcome to icliniq.com. There is a window period of three months after an exposure in which the HIV antibody test may come negative, but six months is a good enough time for the test to become reliable. Ashwagandha does not affect the test. Even if you have autoimmune disease, it means you ...  Read Full »

I married my first cousin. Will my child be affected genetically?

Query: Hi doctor, I have married my first cousin, daughter of my maternal uncle. I would like to know, will there be any genetic issue with our future kid. What are the things we need to take care off? Do we need to take any test? Could you please give some guidance on this. Thank you.  Read Full »


Dr. Megha Tuli

Answer: Hi, Welcome to icliniq.com. I understand your situation. Genetic disorders are more likely in such marriages. I am not trying to scare you but if there is any familial disease in your family it would be good to get it checked in early pregnancy. Any autoimmune disease like rheumatoid arthritis, any ...  Read Full »

My blood report is normal, then why do I feel extremely fatigued?

Query: Hi doctor, I am suffering from low-grade fever, hair loss, and extreme tiredness. There is pain and burning sensation in my stomach along with loss of appetite and weight gain. I got my ANA test done and it came positive. My ESR level has increased. All my other test results found to be negative. Pl...  Read Full »


Dr. Hariharan V

Answer: Hi, Welcome to icliniq.com. I went through your reports (attachment removed to protect patient's identity) and observed that there is no autoimmune disease present. Since you have been suffering from multiple joint pains for the past one year, you should have tested for rheumatoid arthritis (RA) ...  Read Full »

Will recurrent fever occur in a patient with gastritis?

Query: Hi doctor, I am a medical student and my query is regarding my father. My father is suffering from fever, chills and rigor every month along with gastric problem. For gastritis, I am treating him with PPI and Sucralfate. He had similar attack 15 days back. Since I had no clue about the cause, I gave...  Read Full »


Dr. Hariharan V

Answer: Hi, Welcome back to icliniq.com. Though your dad is not having cough or cold that accompanies fever, his symptoms suggest that, it can be due to allergy or post-chikungunya syndrome. Did your dad affected with chikungunya recently? If so, then he might have recurrent fever along with joint pain. Thi...  Read Full »

ask-doctor-img Ask a Doctor Online

* Your first query consult is free!

Search for a Health Issue



Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.