Common "Biopsy" queries answered by top doctors | iCliniq

Biopsy

Biopsy is a diagnostic test which is ordered for the confirmation of diagnosis in certain conditions. In this procedure, a sample of the problematic tissue is removed from the body and sent to a laboratory to be observed under a microscope. There are different types of biopsies based on the procedure used to remove the tissue as well as extent of removal.

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Could delayed breast specimen testing affect the results?

Query: Hello doctor, If a breast specimen is sent to the laboratory for routine histopathology and the breast panel was delayed by three hours, will there be a problem in running the tests? Will the breast panel not be processed because of the delay?  Read Full »


Dr. Utkarsh Sharma

Answer: Hello, Welcome to icliniq.com. I understand your concern and will definitely help you out. A breast specimen should be kept in formalin fixative within one hour of resection for optimal immunohistochemistry (breast panel) results. The most recent guidelines for ER (estrogen receptor), PR (progeste...  Read Full »

My wife’s biopsy report shows grade 2 breast cancer. Kindly help.

Query: Hi doctor, This is for my wife's breast cancer report. I want your opinion on the case and pathology report. As you can see in the biopsy report, it is the grade 2 ( T3, N1, M1). Will it be the same as the specimen after the surgery? Can biopsy show distant metastasis? And lump node? Please advise. ...  Read Full »


Dr. Utkarsh Sharma

Answer: Hi, Welcome to icliniq.com. I understand your concern. I have seen the attached reports (attachments removed to protect the patient's identity). The Nottingham scale is used to classify the grade of the tumor. A score is given according to histology. The higher the score, the poor is differentiati...  Read Full »

Are salivary gland tumors of serious concern?

Query: Hi doctor, My biopsy report reads like this. Please comment. Sections examined show a tumor composed of oncocytic cells arranged in cribriform, cystic, and papillary architecture. Comedonecrosis is present within the cysts. Most of the tumor in the biopsies is in situ. Immunohistochemistry was attem...  Read Full »


Dr. Utkarsh Sharma

Answer: Hi, Welcome to icliniq.com. I have read the description of the biopsy you have provided and will help you regarding it. I must emphasize that before commenting on anything, I must know the site (organ) of the biopsy performed that you have not mentioned. Similar descriptions may have different inter...  Read Full »

What does my biopsy report suggest?

Query: Hello doctor, I have attached my biopsy report. Can you confirm if I am suffering from Crohn's disease? If not, can the report be wrong? Thank you.  Read Full »


Dr. Utkarsh Sharma

Answer: Hi, Welcome back to icliniq.com. I understand your concern and will help you regarding it. I have seen the attached report (the attachment was removed to protect the patient’s identity). The histopathological features described are highly indicative of inflammatory bowel disease (IBD) or could b...  Read Full »

Will biopsy report of tumor change while performing craniotomy for the second time?

Query: Hello doctor, Recently my mother had a craniotomy for tumor removal. Last year she had a craniotomy as well, and it was diagnosed as glioblastoma. But this time, the biopsy report says it is anaplastic astrocytoma. The oncologist says the report is wrong. I am attaching the report below. Please giv...  Read Full »


Dr. Utkarsh Sharma

Answer: Hello, Welcome to icliniq.com. I understand your concern and will help you regarding it. I have assessed the attached histopathology report thoroughly (attachments removed to protect the patient's identity). First of all, I would like to tell you that a pathologist gives the diagnosis based on the...  Read Full »

Is a biopsy report essential when Corhn's signs are present during an abdominal surgery?

Query: Hello doctor, I had small bowel obstruction on the twenty-seventh of last month. They took out the appendix and attached fat tissue. They also found fluid in the stomach pelvis and cul-de-sac. I have lived with really bad constipation for some time tried everything to decrease it. I also have been ...  Read Full »


Dr. Utkarsh Sharma

Answer: Hello, Welcome to icliniq.com. I understand your concern and will help you regarding it. I have assessed the attachments thoroughly (attachments removed to protect the patient's identity). The histopathology report mentions in interpretation, "Appendicular mucosa with minimal focal acute inflammat...  Read Full »

Will biopsy report of DCIS predict hormone receptor status?

Query: Hi doctor, I had a biopsy and I was diagnosed with DCIS. The sample was taken and the pathology report did not show any information about hormone receptor status. I was recommended for surgical excision. I did a lumpectomy and the pathology report came back with the absence of cancer. Can a biopsy ...  Read Full »


Dr. Utkarsh Sharma

Answer: Hi, Welcome to icliniq.com. I shall definitely resolve your concern. When there is no tumor tissue, then it is impossible to know hormone receptor status. On understanding your concern, you have undergone a breast conservative surgery, in which the surgeon has removed the tumor and a small amount of...  Read Full »

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