Bone Marrow Transplantation

Bone marrow transplantation is done to replace bone marrow that has been damaged by infection, disease, or chemotherapy. Conditions that may require bone marrow transplantation are aplastic anemia, leukemia, lymphoma, multiple myeloma, congenital neutropenia, sickle cell anemia, and thalassemia.

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Please suggest how to proceed with the blood cancer treatment for my 8-year-old son.

Query: Hi doctor,My son is eight and a half years old. From his birth, he is having a cold and cough problem. After that, we took CBC and it came back normal. But his WBC was around 22300 till three months from birth. After that, he was unable to walk and got a severe fever, cold, and shivering. I consulte...  Read Full »


Dr. Durairaj Arjunan

Answer: Hi, Welcome to icliniq.com. Your son can have leukemia and there are many types of leukemia. It cannot be confirmed only by doing CBC (complete blood count). There are multiple tests to be done. A fluid test will not show a positive result even in a single test. It has to be repeated. He needs...  Read Full »

Can multiple myeloma be diagnosed only by doing blood tests and X-rays?

Query: Hi doctor, I am a 63 year old male. I have been recently diagnosed with multiple myeloma. My doctor, who is listed as a hematologist or oncologist, said that I must undergo chemotherapy asap. His diagnosis was based solely on bloodwork and a full skeletal x-ray. There was no MRI or PET scan or bone...  Read Full »


Dr. Sagar Ramesh Makode

Answer: Hi, Welcome to icliniq.com. Blood work can strongly suggest myeloma; however, marrow biopsy is needed. But, one can fairly be sure about the diagnosis. Before starting treatment one will need the bone marrow biopsy. Also, bony lesion if visible on x-ray, then one may proceed without MRI or PET scan....  Read Full »

How to treat low blood and bone marrow levels in a 13-year-old girl?

Query: Hello doctor, This query is for my 13-year-old girl. She has a weakness, and CBC revealed poor results. We had a consultation at a hospital, and the doctor gave her Danazol 200 for two months, Quercetin and Renerve plus. The test result suggests aplastic anemia. MMC sensitivity was positive. W...  Read Full »


Dr. Sugreev Singh

Answer: Hi, Welcome to icliniq.com. I can understand your concern. I have checked the reports (attachment removed to protect patient identity), and as per reports, she is not sensitive to Mitomycin C. Mitomycin C is used to treat various unwanted cell growth or tissue growth, such as in the stom...  Read Full »

Is bone marrow transplantation necessary in acute leukemia patient?

Query: Hello doctor, A 27-year-old female has acute leukemia (ALL). Her vision is lost because of the presence of malignant cells in the brain now but her treatment was finished six months back. Previously she got relapsed CSF 13 months back when her maintenance phase was going on. The doctor gave high do...  Read Full »


Dr. Mahmoud Ahmed Abelrahman Abouibrahim

Answer: Hi, Welcome to icliniq.com. Acute lymphoblastic leukemia has a very high relapse rate in adults (about 60 %), the higher the white cell count, the worser the prognosis. Those with Philadelphia chromosome (chromosomal abnormality) have poor prognosis and bone marrow transplantation is required. Rel...  Read Full »

Can beta-thalassemia minor be treated?

Query: Hi doctor, One of my daughters has got beta thalassemia major and G6PD deficiency. Is there any treatment for her? Please advice.  Read Full »


Dr. Geetha Priyadarsini Kamminana

Answer: Hello, Welcome to icliniq.com. Beta thalassemia major includes a hereditary disorder and is due to genetic deficiency of beta globin chains of hemoglobin. It is transfusion dependent anemia.Management of beta thalassemia major includesChronic transfusion to maintain hemoglobin at the range of 9-10 ...  Read Full »

How is the prognosis of refractory T-all pulmonary Koch's disease?

Query: Hi doctor, My friend was diagnosed with refractory T-all pulmonary Koch's with organized pericardial collection. He was admitted in a hospital and now they discharged him and advised further treatment. Please give me valuable advice. What is the current condition? And how much is the percentage of l...  Read Full »


Dr. Prakash H Muddegowda

Answer: Hi, Welcome to icliniq.com. Based on your query and attached reports (attachment removed to protect patient identity), my opinion is as follows: Pulmonary tuberculosis is under control and continuation of therapy is necessary. However, the main problem is leukemia, which is not responding ...  Read Full »

Please suggest treatment for thalassemia major.

Query: Hi doctor, I am a thalassemia major patient. My spleen size is 21. How to reduce my spleen size? And also I want to increase my weight? My age is 21. How much percentage risk is present in the unrelated donor stem cell transplant? My ferritin is 1500 and weight is 48 kg. Please suggest some solution...  Read Full »


Dr. Sumit Srivastava

Answer: Hi, Welcome to icliniq.com. At present there is no way to reduce the spleen size. Diet for thalassemia major patient should include plenty of fruits and vegetables and protein rich diet. Taking vitamin C supplements will help to increase the immunity of the body. Bone marrow transplantation is a...  Read Full »

Is it necessary to do bone marrow transplant for acute leukemia?

Query: Hello doctor,My friend's brother is diagnosed with blood cancer and has gone through first chemotherapy three weeks ago. According to acute leukemia immunophenotyping by flow cytometry report, morphologic and immunophenotypic findings are consistent with acute myeloid leukemia. Immunophenotypic find...  Read Full »


Dr. Parth R Goswami

Answer: Hi, Welcome to icliniq.com. Sorry to hear about his ill health. Let me tell you that after seven days of the first round of chemotherapy, bone marrow biopsy should be done to check for the percentage of the blast. Ideally, it should be less than 5 % blast after the first round of chemotherapy. The...  Read Full »

Is it fine to have itchy throat and stuffy nose after allogenic bone marrow transplant?

Query: Hello doctor, I am an 18-year-old girl. I have been a patient of beta thalassemia major. Recently allogenic bone marrow transplant was conducted (70 days since transplant). Before this, I had no history of any allergy or rash or another disease other than thalassemia. Recently, I have felt itchy thr...  Read Full »


Dr. Parth R Goswami

Answer: Hi, Welcome to icliniq.com. Your symptoms are suggestive of upper respiratory tract infection, possibly allergic inflammation. I suggest you investigate with CBC for primary work up. Meanwhile, a decongestant can be prescribed for your symptoms. You can drink warm water that helps in the soothing ...  Read Full »

For thalassemia major, when would my son require his first blood transfusion?

Query: Hello doctor, My son is 15 months old and has been diagnosed with thalassemia major. My only question is when he would require his first blood transfusion? Because typically people feel strong symptoms of anemia and need medical help when Hb goes below 6. But, my child has Hb of 3.7 probably for ove...  Read Full »


Dr. Deepak Patel

Answer: Hi, Welcome to icliniq.com. I can understand your concerns. The definite management of thalassemia is bone marrow transplant. For this HLA - human leukocyte antigen) matching is done and if possible this is the best treatment available right now. The second one is a regular blood transfusion. We usu...  Read Full »

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