Common "Bone Marrow Transplantation" queries answered by top doctors | iCliniq

Bone Marrow Transplantation

Bone marrow transplantation is done to replace bone marrow that has been damaged by infection, disease, or chemotherapy. Conditions that may require bone marrow transplantation are aplastic anemia, leukemia, lymphoma, multiple myeloma, congenital neutropenia, sickle cell anemia, and thalassemia.

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Is it necessary to do bone marrow transplant for acute leukemia?

Query: Hello doctor, My friend's brother has been diagnosed with blood cancer and underwent his first chemotherapy three weeks ago. According to the acute leukemia immunophenotyping by flow cytometry report, morphologic and immunophenotypic findings are consistent with acute myeloid leukemia. Immunophenoty...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to Sorry to hear about his ill health. Let me tell you that after seven days of the first round of chemotherapy, a bone marrow biopsy should be done to check for the percentage of the blast. Ideally, it should be less than a five percent blast after the first round of chem...  Read Full »

My son has thalassemia major. Please suggest.

Query: Hello doctor, My son is 15 months old and has been diagnosed with thalassemia major. My only question is when he would require his first blood transfusion? Because typically people feel strong symptoms of anemia and need medical help when Hb goes below 6. But, my child has Hb of 3.7 probably for ove...  Read Full »

Dr. Deepak Patel

Answer: Hi, Welcome to I can understand your concerns. The definite management of thalassemia is bone marrow transplant. For this HLA - human leukocyte antigen) matching is done and if possible this is the best treatment available right now. The second one is a regular blood transfusion. We us...  Read Full »

Please suggest treatment for thalassemia major.

Query: Hi doctor, I am a thalassemia major patient. My spleen size is 8.2 inch. How to reduce my spleen size? And also I want to increase my weight? I am 21 years old. What percentage of risk is present in an unrelated donor stem cell transplant? My ferritin is 1500 µg/L and weight is 106 lbs. Please sugg...  Read Full »

Dr. Srivastava, Sumit

Answer: Hi, Welcome to At present there is no way to reduce the spleen size. Diet for thalassemia major patient should include plenty of fruits and vegetables and protein rich diet. Taking vitamin C supplements will help to increase the immunity of the body. Bone marrow transplantation is a cu...  Read Full »

Please suggest how to proceed with the blood cancer treatment for my 8-year-old son.

Query: Hi doctor, My son is 9 years old. From his birth, he is having a cold and cough problem. After that, we took CBC and it came back normal. But his WBC was around 22300 till three months from birth. After that, he was unable to walk and got a severe fever, cold, and shivering. I consulted a child spe...  Read Full »

Dr. Durairaj A

Answer: Hi, Welcome to Your son can have leukemia and there are many types of leukemia. It cannot be confirmed only by doing CBC (complete blood count). There are multiple tests to be done. A fluid test will not show a positive result even in a single test. It has to be repeated. He needs to ...  Read Full »

Is bone marrow transplantation necessary in acute leukemia patient?

Query: Hello doctor, A 27-year-old female has acute leukemia (ALL). Her vision is lost because of the presence of malignant cells in the brain now but her treatment was finished six months back. Previously she got relapsed CSF 13 months back when her maintenance phase was going on. The doctor gave high do...  Read Full »

Dr. Mahmoud Ahmed Abdelrahman Abouibrahim

Answer: Hi, Welcome to Acute lymphoblastic leukemia has a very high relapse rate in adults (about 60 %), the higher the white cell count, the worser the prognosis. Those with Philadelphia chromosome (chromosomal abnormality) have poor prognosis and bone marrow transplantation is required. Rel...  Read Full »

Can multiple myeloma be diagnosed only by doing blood tests and X-rays?

Query: Hi doctor, I am a 63 year old male. I have been recently diagnosed with multiple myeloma. My doctor, who is listed as a hematologist or oncologist, said that I must undergo chemotherapy asap. His diagnosis was based solely on bloodwork and a full skeletal x-ray. There was no MRI or PET scan or bone ...  Read Full »

Dr. Sagar Ramesh Makode

Answer: Hi, Welcome to Blood tests can provide compelling indications of myeloma; however, a marrow biopsy remains essential for confirmation. While a diagnosis can be reasonably presumed, it's imperative to undergo a bone marrow biopsy prior to commencing treatment. If visible on an X-ray, bo...  Read Full »

How is the prognosis of refractory T-all pulmonary Koch's disease?

Query: Hi doctor, My friend was diagnosed with refractory T cell ALL pulmonary Koch's with the organized pericardial collection. He was admitted to a hospital and now they discharged him and advised further treatment. Please give me valuable advice. What is the current condition? And how much is the percen...  Read Full »

Dr. Prakash. H. M.

Answer: Hi, Welcome to Based on your query and attached reports (attachment removed to protect patient identity), my opinion is as follows: Pulmonary tuberculosis is under control and continuation of therapy is necessary. However, the main problem is leukemia, which is not responding to tre...  Read Full »

How to treat low blood and bone marrow levels in a 13-year-old girl?

Query: Hello doctor, This query is for my 13-year-old girl. She has a weakness, and CBC revealed poor results. We had a consultation at a hospital, and the doctor gave her Danazol 200 for two months, Quercetin and Renerve plus. The test result suggests aplastic anemia. MMC sensitivity was positive. W...  Read Full »

Dr. Sugreev Singh

Answer: Hi, Welcome to I can understand your concern. I have checked the reports (attachment removed to protect patient identity), and as per reports, she is not sensitive to Mitomycin C. Mitomycin C is used to treat various unwanted cell growth or tissue growth, such as in the stom...  Read Full »

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