HomeAnswersGeneral Medicinecomplete blood countWhat causes high MPV?

What do high MPV and giant platelet in CBC mean?

Share
What do high MPV and giant platelet in CBC mean?

The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

iCliniq medical review team

Published At December 31, 2016
Reviewed AtAugust 17, 2023

Patient's Query

Hello doctor,

My father is 65 years old. Recently, we went for his routine cardio checkup. His doctor suggested a thallium stress test, which was normal. He has been hypertensive for 15 years and is on anti-hypertensive Ramipril 5 mg, Amlodipine 2.5 mg and one diuretic. His BP was high, so the doctor has increased his dose this time. The doctor also asked for CBC. His CBC showed high MPV and giant platelet. What does that mean? I am attaching the report here. It would be really helpful if you go through the whole report and clear my doubt.

Hello,

Welcome to icliniq.com.

I had gone through all the reports posted (attachment removed to protect patient identity). Mean platelet volume suggests the mean volume of single platelet, which is high and is mostly an incidental finding. Some bleeding disorders like functional defects of platelets are associated with giant platelets. Also, in case of increased production of platelets, they are released into circulation before they mature and so, immature platelets will be giant. As there is no history of any bleeding disorder like bleeding from gums and spontaneous petechiae, it does not need further workup. We can do a peripheral smear to look at platelets. But in the present scenario, it does not seem clinically significant.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Naresh Kumar M.
Dr. Naresh Kumar M.

Internal Medicine

Community Banner Mobile
By subscribing, I agree to iCliniq's Terms & Privacy Policy.

Ask your health query to a doctor online

General Medicine

*guaranteed answer within 4 hours

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.

This website uses cookies to ensure you get the best experience on our website. iCliniq privacy policy