HomeAnswersNephrologycreatinineMy creatinine level is 537 mg/dL, with symptoms. What it means?

What does a urine creatinine level of 537 mg/dL indicate?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

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iCliniq medical review team

Published At December 18, 2022
Reviewed AtJanuary 23, 2024

Patient's Query

Hello doctor,

I am 24 years old. I have fatigue, nausea, back pain, pallor, weakness, and dark urine. My creatinine urine is 537 mg/dL. What does this mean? eGFR has dropped from 120 to 86 mL/minute.

Kindly help.

Hello,

Welcome to icliniq.com.

Thank you for your query.

I understand your concern and reviewed your reports (attachment removed to protect the patient's identity). Your serum creatinine is normal, which gives an eGFR of 86. eGFR should be more than 60, which is in your case. You were concerned about urine creatinine of 537mg/dL. This carries no significance as it can vary per water and protein intake. If one takes plenty of fluids, urine creatinine levels will decrease. What matters is the serum creatinine level which is normal in your case. Your urine protein level is also normal.

I hope this has helped you. Thank you.

Patient's Query

Hello doctor,

Thank you for your reply.

Should I be concerned if my serum creatinine is changing rapidly? My normal is around 75. On Friday, it was 0.95, and yesterday, it was 1.03.

Hello,

Welcome back to icliniq.com.

Day-to-day variation of serum creatinine normally is around 10 to 15 percent. So if serum creatinine varies between 0.95 to 1.03, it is okay. However, if serum creatinine is continuously increasing, it is worrisome. You had pain abdomen and dark urine, and I would like to know what happened to that. Do you have symptoms like nausea, vomiting, pain abdomen, and decreased urine output? If you do not have any symptoms and serum creatinine is varying but not continuously increasing, you do not have to worry much. I would also suggest you to avoid painkillers or any unnecessary over-the-counter drugs.

I hope this has helped you. Thank you.

Patient's Query

Hello doctor,

Yes, serum creatinine has continuously increased over the past few days from 0.75, 0.95, and 1.03. And I have nausea, back pain, and low urine output. Also no UTI according to urine analysis. I went to ER but was sent home and informed that it was just dehydration. So I will attach blood work from the ER.

Hello,

Welcome back to icliniq.com.

I reviewed your laboratory reports from ER (attachment removed to protect the patient's identity). Your urine is concentrated, and the increase in serum creatinine looks to be due to dehydration only. The issue in your case is why you are having dehydration and nausea, and back pain. You need to take care of hydration. But if you persist with nausea and back pain, I suggest you visit the specialist.

I hope this has helped you. Thank you.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Manzoor Ahmad Parry
Dr. Manzoor Ahmad Parry

Nephrology

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