I suffer from anxiety and depression that persists despite taking medications. Why?

Q. How to treat anxiety and depression that persists despite taking medications?

Answered by
Dr. Vishal Anilkumar Gandhi
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Sep 19, 2023

Hello doctor,

I am a 35-year-old male with a weight of 147.71 lbs and a height of 5 feet and 9 inches. I have been diagnosed with depression along with anxiety. I was prescribed Clonazepam 0.5 mg initially and later 0.25 mg with Escitalopram 20 mg. My anxiety is under control to a good extent but my depression seems to persist. I have been switched to Prozac 20 mg with 0.25 mg of Clonazepam. I am mainly describing here the main symptoms which are disturbing me and persistent for almost two years. I have emotional numbing and dissociation from everything. It seems like I am just passing time and not living it. I am living my life totally in hell. I do not have any heart and mind connections. I do not have any motivation. I have very low energy. I feel sleepy all the time even after eight to ten hours of sleep. I do not have much confidence. I want to fix all these issues at the earliest as these are affecting me badly along with my work life. Please advise.



Welcome to icliniq.com.

Thank you for taking help from a psychiatrist. I can understand your situation. You may have a major depressive disorder with anxiety. There is non-pharmacological management for it, you should try to follow the below guidelines to deal with it. It will help you.

  1. You should do exercises daily for 30 to 45 minutes like at least going for a walk. it will boost confidence.
  2. You should do meditation for 20 minutes daily, just sit in one place in a comfortable position and try to concentrate on your normal breathing, don't stop or force yourself to stop your thoughts, just let it be. it will relax you.
  3. You should eat healthy home-cooked foods, and avoid junk foods.
  4. You must drink enough water.
  5. You should spend quality time with friends and family daily or do video calls if you are living away from your family.
  6. You should spend time on creative hobbies like reading good books, writing journals, painting, drawing, and learning new skills or language or musical instruments.
  7. You should take enough even to eight hours of sleep daily.
  8. You must avoid tobacco or alcohol or any substance abuse.
  9. Live your life, do not just spend it.
  10. Be bold and confident.
  11. You must increase the dose of your Prozac (Fluoxetine hydrochloride) if you do not improve. You do not need to switch medication without reaching to optimal dose.

You must do the following blood reports as its abnormality may affect your depression.

  1. CBC (complete blood count).
  2. RBS (random blood sugar).
  3. Thyroid profile.
  4. Vitamin B12.
  5. Vitamin D3.

I hope that you get your answer. Please, let me know if you want some help.

Thank you.

Investigations to be done:

CBC (complete blood count).

RBS (random blood sugar).

Thyroid profile.

Vitamin B12.

Vitamin D3.

Was this answer helpful?


Same symptoms doesn’t mean you have the same problem. Consult a doctor now!

Related Questions:
Depression and Burnout in Athletes - An Overview

Depression, a mental disorder, is defined by persistent sadness, despair, and helplessness ...   Read full

Mirap and Clonazepam prescribed for anxiety and depression, Is it fine to take?

Hello Doctor, I am suffering from anxiety and depression ... Mirap is a Mirtazapine which is indicated for depression ...   Read full

Depression - Awareness, Self-Diagnosis, and Treatment Modalities

According to statistics provided by WHO, depressive disorders are predicted to be the major cause of mortality and morbidity in the world in the next three years ...   Read full

Also Read Answers From:

ideaComprehensive Medical Second Opinion.Submit your Case

Also Read

PCOS and Liver Problems
The hormonal imbalances in polycystic ovary syndrome could cause liver diseases. Read the article to know the relationship between these medical conditions.  Read more»
Inferior Alveolar Nerve Lateralization Technique
The inferior alveolar nerve lateralization technique is a surgical lateralization technique to reposition the nerve. Read the article to know more about this.  Read more»
COVID-19 and Ebola: Similarities and Differences
This article gives a comparison and broader overview of the outbreak of the two deadliest diseases that showed a greater incidence over the last two decades.  Read more»

Ask your health query to a doctor online?

Ask a Psychiatrist Now

* guaranteed answer within 4 hours.

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.