HomeAnswersDiabetologydiabetesWill oral anti-diabetic medications cause drastic weight loss and kidney damage?

As diabetic medicines are causing weight loss, can I switch to insulin to overcome it?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

Dr. Vinodhini J.

Published At March 18, 2020
Reviewed AtJanuary 18, 2024

Patient's Query

Hello doctor,

I am a diabetic. My weight is 152 pounds and my height is 5' 9". My PP glucose level is 150 to 210 mg/dL. I am taking Glynase MF one in the morning, tablet Exermet GM 501 one in the evening. My BP is normal. I tested my glucose levels today and postprandial glucose level is 204 mg/dL. I am interested in taking Insulin replacing oral medicine. I heard that oral medicines cause weight reduction and dangerous for kidneys.

Hello,

Welcome to icliniq.com.

The Metformin component of the oral anti-diabetic medications aids in weight loss and is usually preferred in overweight candidates. But, there are other medications that do not lead to weight loss, so, you can definitely ask your physician to shift you to such medication. Also, just like all medications have side effects, long term studies in patients taking oral anti-diabetic medications, have shown deteriorated kidney function. Many people are not compliant in keeping up with daily injections of Insulin, also the risk of hypoglycemia is higher with insulin. Hence, not many people prefer it. If you feel you can cope up with it, please speak to your local physician or diabetologist. They would make a chart depending on your daily sugar levels, as to how much units of insulin would you require. Also, they would educate you regarding rotation of sites, for taking the insulin injections, how and when to take them. Also, do not forget to ask your physician to explain the symptoms of hypoglycemia and also to tell you, when exactly should you be taking the insulin injections (before food, during food, morning or night basal dose) depending on its duration of action. I hope this helps.

Patient's Query

Thank you doctor,

I have much weight loss and I fear renal problems. All my costly cloths are getting loose and waste thereof looking shabby. Also, I request you to prescribe basic level insulin indicating nano injections.

Hello,

Welcome back to icliniq.com.

I regret telling you, that starting insulin is a very critical step and should be followed by appropriate knowledge of insulin and its administration. Being an online portal, my assistance to you is very limited and advising you insulin doses, would be outside my boundaries simply because its window margin of error is very small. I hope you understand. In case you were already using insulin, I would be able to adjust your doses according to your blood sugar levels, but since we are starting it for the first time, you must understand the gravity of the situation. Inadequate dosage would be of no help to you and an excess dosage might land you into hypoglycemia or fainting episode. Hence, I would urge you to please meet a local physician in person. I would always be here to guide you, in case you need any other help.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Krutika Shrikant Ingle
Dr. Krutika Shrikant Ingle

Diabetology

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