Dosage And Duration

Dosage is referred to as the frequency or the number of times a prescribed drug dose to be taken in a prescribed dosage form. Dosages are mentioned as OD (once daily), BID (twice daily), TID (thrice daily) or as 1-0-1 (morning and night), 1-1-1 (morning, afternoon, and night), etc. There are various dosage forms such as tablets, patches, ointments, etc. Specialized dosage forms are dispersible, extended-release, chewable tablets, etc. Duration is referred to as the number of days the prescribed dosage to be taken by the patient. Duration of action of a drug is the amount of time the effect of the drug lasts.

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What is the cause of chills and vomiting while taking medicines for hypertension?

Query: Hello doctor,The patient suddenly feels chills all over the body after taking a beta blocker, calcium channel blocker, Clopidogrel, Aspirin, and Atorvastatin. She is unable to stand, walk or move. The BP monitor shows error and is not showing any BP value. When checked in sphygmomanometer there is K...  Read Full »

Dr. Muhammad Majid Hanif

Answer: Hello, Welcome to I have reviewed your query and can understand you are worried about a patient who is feeling a bunch of symptoms. Thanks for adding the detailed medications she is taking. From her overall scenario, based on the information provided, it seems she may be having issue...  Read Full »

My BP is well under control. Can I decrease the dosage of my medicines?

Query: Hello doctor, I am a patient of hypertension and anxiety, taking treatment for the last two years. Presently, my BP is well under control (average BP 115/70) and pulse varies between 75 to 95 BPM. Presently, I am taking Telma CT (80 + 12.5) and Embeta-XR 50 daily & Esnax Plus (Escitalopram + Clo...  Read Full »

Dr. Muhammad Majid Hanif

Answer: Hello, Welcome to If you are taking this medication regularly and the blood pressure and pulse readings are current or latest, then it would not be a good idea to change the medications or dosage of some of them. Your weight (BMI) should also be within healthy limits with no 'centra...  Read Full »

I had a medical error in taking Cladribine. What can I expect?

Query: Hello doctor, I had a medical error in taking Cladribine infusion within 30 minutes for four days out of seven days. The treatment is supposed to be taken 24 hours a day. What is the procedure currently required and is there any danger in the short-term and long-term and whether the treatment was ta...  Read Full »

Dr. Singh Smrita

Answer: Hello, Welcome to Cladribine is an antineoplastic drug used mainly in hairy cell leukemia. It is also used in other hematolymphoid malignancies. Since you have not mentioned the condition you are receiving the drug for, I am assuming that it is for hairy cell leukemia. The main advers...  Read Full »

How to reduce the dosage and gradually stop my medicines without side effects?

Query: Hello doctor,I am a 23 year old male. I want to quit my medicines permanently. I am taking Valkem OD 500, Soltus 100 mg, Flunil 20, and Ativan 2 mg. How to reduce the doses and completely stop taking these medications without any side effects?  Read Full »

Dr. Ashaq Hussain Parrey

Answer: Hello, Welcome to I went through your post. You are on Divalproex (Valkem) which is used for epilepsy; in addition, you are on antidepressants and antipsychotic meds. Firstly, if you have a seizure disorder, for which you are taking Valkem, then your EEG (electroencephalogram) shoul...  Read Full »

I want to take Manforce (Sildenafil) 50 mg. What are the dosage and duration?

Query: Hi doctor, I want to take Manforce (Sildenafil) 50 mg. Is that advisable? If so, when should I take it?  Read Full »

Dr. Sameer Kumar

Answer: Hello, Welcome to I understand your concern. It is a tablet, Sildenafil (Viagra). These are the instructions to use it. It is orally taken in the form of a tablet. Take it an hour before copulation for best results. However, you can take any time from 4 hours to 30 minutes before the...  Read Full »

Is it safe to change the dosage of heart medicines to once every two days?

Query: Hi doctor,I am a 49 year old male. Five years ago, I got two stents on the left. Actually, my heart was good only 30 % block. I take Vitoryn and Aspirin until now. I started having arrhythmia two years ago. AF comes out once every one and a half months for two to four hours. When AF attacks, I canno...  Read Full »

Dr. Muhammad Majid Hanif

Answer: Hello, Welcome to I have reviewed your health query and can well understand you are worried about your heart health. I would not say to stop Xarelto (Rivaroxaban) and/or Cordarone (Amiodarone) as these are very important medications and you need them. For stent patients, Xarelto reduc...  Read Full »

Is it fine to increase the Spironolactone dose after taking it for four weeks?

Query: Hi doctor, I have had chronic acne for the past ten years and recently I have been prescribed Spironolactone. I am taking 50 mg of Spironolactone once daily as prescribed. Currently, I am also on Methylphenidate. According to my prescription label, after four weeks, I am recommended to start taking ...  Read Full »

Dr. Sandhya Narayanan Kutty

Answer: Hi, Welcome to I understand your concern. As advised by your doctor, the Spironolactone tablet is to be used once daily for four weeks as per the history provided from your end, and I would like to advise you the same. It takes time for our body to get used to a specific dosage befor...  Read Full »

I have been on tablet Fluconazole 500 mg four times daily for a soft tissue infection. Can I reduce the dosage to twice daily?

Query: Hello doctor, I have been on capsule Flucloxacillin 500 mg four times a day for a soft tissue infection. Unfortunately, the condition has recurred, and I am staying in abroad. Can I reduce the dosage of the medicine to twice daily? Kindly help.  Read Full »

Dr. Muhammad Zohaib Siddiq

Answer: Hi, Welcome to I understand your concern. Capsule Flucloxacillin has a short half-life, so it should be taken six hourly. However, I suggest taking it four times a day or thrice daily and taking it one or two hours before the meal as food decreases absorption. Kindly revert for more ...  Read Full »

Will missing a dose of Lorazepam cause serious symptoms?

Query: Hello doctor,I have been taking Lorazepam for 25 years. For the last four years, I have been taking 4 mg daily. 2 mg at night for sleep, and the other two split in the day. I only had two today and do not have any for tonight. I will pick up my prescription in the morning. I am concerned if my going...  Read Full »

Dr. Sagar Ramesh Makode

Answer: Hello, Welcome to I understand your concern. It will cause some symptoms like tremors, anxiety, and lack of sleep tonight, but serious side effects will probably not occur, especially if the dose is taken in the late afternoon or evening. Usually, symptoms onset occurs after 24 hours...  Read Full »

What should I do if I have taken seven 500mg crocin(paracetamol) tablets together?

Query: Hi, What should I do if I have taken seven 500 mg crocin tablets together?  Read Full »

Dr. Ignatius Soon

Answer: Hi, Welcome to If you indeed took 7 x 500mg crocin tablets which on the GSK website are paracetamol tablets, your total dose is 7X500mg = 3500mg of Paracetamol. The answer would depend on how heavy you are. Most of the time, the toxic dose is 200mg per kilogram. For example, if you ...  Read Full »

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