Common "Double Marker" queries answered by top doctors | iCliniq

Double Marker

Double marker test is done to access the risk of delivering a child with Down syndrome. It is generally done between 8 and 14 weeks of pregnancy. It is used to detect Down syndrome (trisomy 21) and trisomy 18, which are chromosomal defects.

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Kindly explain my NT scan and double marker test result.

Query: Hello doctor, I am a 34-year-old female. Kindly explain my NT scan and double marker test result. PAAP -A - 3.37 miU/ml, HCG, free beta - 147.00 ng/ml, NT value - 1.40mm, Trisomy 21 - 1:227.  Read Full »


Dr. Mavani Jimesh Himatbhai

Answer: Hello, Welcome to icliniq.com. Let me explain to you first why this report is done and what it is about. Basically it is a screening test and results of that do not indicate that baby has a problem. It just indicate that what are the chances of your baby to have some congenital anomalies like Down...  Read Full »

Kindly explain my nuchal translucency scan and double marker blood test reports.

Query: Hello, Welcome to icliniq.com. Kindly explain my nuchal translucency scan and double marker blood test reports in details. I am very worried due to in NT scan nasal bone could not be discretely seen. Gestational Age (as per USG) is 12 weeks and three days. All report attached here for your guidanc...  Read Full »


Dr. Balakrishnan R

Answer: Hello, Welcome to icliniq.com. I do not see any problem in your reports (attachment removed to protect patient identity). Your blood reports and scan are within normal limits. Ultrasound scan is done at this 11 to 14 weeks to find out the most common genetic abnormality of the baby- Down syndrome....  Read Full »

What do my NT scan and double marker reports say?

Query: Hello doctor, I am a 31 year old female. I am 12 weeks pregnant. I have received my NT scan and double marker reports. Below are the details: NT 0.70 mm, trisomy 21 and NT 1:675, trisomy 13/18.  Read Full »


Dr. Balakrishnan R

Answer: Hello, Welcome to icliniq.com. Let me start by saying that you and your baby are absolutely fine. First of all, 31 years is not at all a risk factor. Only after 35 years, the risk of these genetic problems increases a lot, much more after 40 years. These factors are calculated using an age correl...  Read Full »

Are my NT scan reports normal?

Query: Hello doctor, I had the NT scan at 11 weeks and 4 days and the NT was 3.3 mm. After that, I got the double marker test done which came back normal, with a risk of 1:624 for T21 and 1:685 for T13 and T18. I was asked to do the NT scan again and at 12 weeks and 2 days, the NT measured 2.8 mm. Also, th...  Read Full »


Dr. Neha Rathod

Answer: Hello, Welcome to icliniq.com. I have gone through your query. There is nothing to worry about. All the reports are fine and your baby has no anomaly. So, relax and do not worry. You need not go for any further invasive procedures like amniocentesis. Just get your TIFFA (targeted imaging for fetal...  Read Full »

Can a temperate pool at 98 F affect the baby during pregnancy?

Query: Hello doctor, I found out that I am pregnant, and the next day I went to a spa. Knowing that hot tub and sauna are not good for me, the lady at the spa told me to go to the temperate pool, which was 98 F. I went for five minutes, and now I am so scared. Did I do something wrong? Please help.  Read Full »


Dr. Sonal Prasad

Answer: Hello, Welcome to icliniq.com. Do not worry, sauna is to be avoided in pregnancy, but not ones with temperature as body temperature. The lady at the spa was wise. Make sure you take your antenatal vitamins throughout pregnancy. For more information consult a doctor soon.   Read Full »

Is it risky if the NT scan shows 3 to 5 mm thickness in a three-month pregnant woman?

Query: Hello doctor, I am a 33 year old female, who has a 5 year old baby girl. I had two miscarriages, one two years back at 11 weeks, and one last year at nine weeks. Now, I am three months pregnant, and I had a NT scan, which showed a thickness of 3 to 5 mm. Is this a case of high-risk pregnancy? Does i...  Read Full »


Dr. Balakrishnan R

Answer: Hi, Welcome to icliniq.com. Let me put forth few facts. Your age is in normal limits and not in high-risk for anomalies or genetic problem. Only after 37 to 40 years it is high-risk. You do not seem to have any medical complications. You have one 5 year old child, so the chance of next healthy preg...  Read Full »

What does my double marker blood test indicate?

Query: Hi doctor, I am 12 weeks 5 days pregnant. I got my NT scan and double marker blood test results. NT value 1.1 mm, free b-hCG 1.52 MOM, PAPP-A 0.37 MOM, trisomy 21+NT risk 1:1132, trisomy 21 1:169, trisomy 13/18+NT. In urine culture, there is no significant growth observed after 48 hours. I am curren...  Read Full »


Dr. Mavani Jimesh Himatbhai

Answer: Hello, Welcome to icliniq.com. I have seen the report completely (attachment removed to protect patient identity). Your report is normal and there is no need to worry. If you want a detailed explanation about the report, then here you go. There are some genetic syndromes, which are happening worl...  Read Full »

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