Down's Syndrome

Down's syndrome, otherwise called trisomy 21, is a genetic disorder that results from the presence of an extra copy of chromosome 21. This chromosomal change results in physical characteristics like small head, short neck, poor muscle tone, wider and flat nasal bridge, and small ears. It also results in cognitive impairment and memory problems.

Recently Answered Questions Recently Answered Questions

All the answers published in this website are written by Verified medical doctors, therapists and health experts. The Content has been moderated by iCliniq medical review team before publication. Post your medical clarifications on iCliniq by choosing the right specialty and get them answered. Your medical queries will be answered 24/7 by top doctors from iCliniq.

Trisomy 21 is positive in nuchal translucency. What does it indicate?

Query: Hello doctor, My wife is 36-year-old with a height of 5.6 and weight 69.1 kg. She had NT or NB scan and double marker test in obstetrical ultrasound. The nuchal thickness is 1.0 mm. Presence of nasal bone. DV flow is normal, but in double marker test, free beta hCG is 46.20 and PAPP-A is 2.58. Triso...  Read Full »


Dr. Nadia Khan

Answer: Hello, Welcome to icliniq.com. 1 in 250 means that if we take 250 women of the same results as your wife had then only one will have a baby with Down syndrome. So this is the explanation of the calculated risk of down syndrome. Secondly, NT (nuchal translucency) and blood tests which she underwen...  Read Full »

My trisomy 21 report value is 1:250. Was it normal?

Query: Hi doctor, I am 12 weeks 5 days pregnant. My NT scan measures 1.6 mm, the double marker PAPP-A is 2.82, and free beta hCG is 36.7 Could you please help with the report? Was it normal? My trisomy 21 is 1:250.  Read Full »


Dr. Nadia Khan

Answer: Hello, Welcome to icliniq.com. 1 in 250 is a high risk for trisomy which means your risk of having a baby with trisomy 21 is 1 out of 250. But this test is only a screening test which means that they just calculate the risk of having a baby with down syndrome. If someone is found at higher risk li...  Read Full »

ask-doctor-img Ask a Doctor Online

* guaranteed answer within 4 hours

Search for a Health Issue



Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.