HomeAnswersNeurologydrug interactionsIs it safe to pair Gabapentin with Metoclopramide?

Is it safe to pair Gabapentin with Metoclopramide?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Answered by

Dr. Ashok Kumar

Medically reviewed by

iCliniq medical review team

Published At October 1, 2017
Reviewed AtAugust 11, 2023

Patient's Query

Hello doctor,

I suffer from chronic migraines, and I take Gabapentin, 1800 mg daily for prevention. Recently, a general practitioner (GP) recommended Metoclopramide, 30 mg daily to help with nausea, but I have yet to take it, as I am concerned about the combination. Is this a safe pair of drugs to use together? Thank you.

Answered by Dr. Ashok Kumar

Hi,

Welcome to icliniq.com. I read your query and understand your concerns. I would like to state that Gabapentin and Metoclopramide have no major interactions and can be taken together. However, there are reports of increased side effects such as giddiness and sedation. Some of the individuals with this combination report difficulty in concentrating and driving. Considering the above facts, I like to advise you to avoid operating any kind of heavy machinery, for example, driving, during the initial three to four days till you are comfortable. Your general practitioner (GP) is right and if the nausea is still problematic, you can opt for Metoclopramide. I hope this answers you. If you have more questions feel free to write back to me. Thanks and regards.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Ashok Kumar
Dr. Ashok Kumar

Geriatrics

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