HomeAnswersHIV/AIDS specialistefavirenzHow to deal with the side effects of Atroiza?

How to manage the side effects of Atroiza with HIV?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

iCliniq medical review team

Published At October 22, 2019
Reviewed AtApril 16, 2024

Patient's Query

Hello doctor,

I am an asymptomatic HIV (Human Immunodeficiency Virus) positive male with a CD4 count of 320. I started on Atroiza and Cotrimoxazole two days back. But yesterday I drunk and could not sleep and sat outside at night because I could not breathe properly. My problem is, I am in holiday now. My night shift job starting is starting soon. I do not think I can cope with these new side effects on this job. I really need this job, but I am afraid to stop the treatment after two days and for the duration of the holidays, as it may make the virus resistant. Please help.

Hello, welcome to icliniq.com.

Atroiza is a combination of three drugs (Efavirenz, Tenofovir DF, Emtricitabine) for the treatment of HIV. Among which, Efavirenz is the drug known to cause such side effects. These side effects of insomnia, vivid thinking, night time issues are temporary and would last for the first two weeks after starting the therapy. It would be advisable not to stop ART (antiretroviral therapy) as there are high chances of developing resistance. You can instead consider replacing Efavirenz with another drug called Nevirapine, which does not have these side effects. Kindly mention your HBsAg, Anti HCV (hepatitis C antibody test), VDRL (venereal disease research laboratory test), and tuberculosis status as they may affect the treatment too.

Treatment plan

Consider replacing Efavirenz with Nevirapine after discussing it with the physician.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Rakesh Kumar Bahunuthula
Dr. Rakesh Kumar Bahunuthula

Dermatology

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