I tested negative for HIV 1/2 combo with a P24 antigen test after having an unprotected oral sex with a sex worker. Should I get PEP?

Q. What are the chances of getting HIV from an unprotected oral sex with a sex worker?

Answered by
Dr. Basti Bharatesh Devendra
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Apr 12, 2023 and last reviewed on: Aug 23, 2023

Hi doctor,

I am a 29-year-old male who got an unprotected blowjob from a sex worker at a massage parlor. I do not know her HIV (human immunodeficiency virus) status, I did oral sex only one time and I did not ejaculate in her mouth. Then she cleaned all with a towel and I washed my penis with soap and water. Later I got HIV 1/2 combo with the p24 antigen test which comes negative. Please help me, should I go for PEP (Post - exposure Prophylaxis)? I am not able to sleep, what should I do?


Hi, Welcome to icliniq.com.

The chances of transmission of HIV (human immunodeficiency virus) by single unprotected oral sex is almost nil unless there are bleeding wounds in the oral cavity. If the person is HIV-negative then there is no chance of transmission of HIV. The HIV antibodies negative test results suggest negative status as of now but are not conclusive for this episode. PEP (post-exposure prophylaxis) may not be needed if the act is limited only to this. Please consult your doctor for further risk assessment and the need for PEP. PEP if needed has to be initiated as early as possible not later than 72 hours of exposure.

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