HomeAnswersInternal Medicinehigh esrI have chronic pain and tiredness for the past three years and, my ESR values are high. Please help.

What would be the cause of raised ESR value?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

Dr. Sneha Kannan

Published At March 15, 2022
Reviewed AtMay 10, 2023

Patient's Query

Hi doctor,

I have been experiencing chronic pain, fatigue, weakness, dizziness, and discomfort for the past three years. I have a high ESR rate. Please help. Thank you.

Hi, Welcome to icliniq.com.

I have read your query and I am sorry for such discomfort. ESR (erythrocyte sedimentation rate) is a non-specific test that does not precisely help to locate the cause or problem in the body rather it gives clue that some kind of inflammation or infection is present in the body. Just based on the ESR value the list of differential diagnoses would be huge. So the test is coupled with other relevant tests depending upon the patient's description of the medical history to rule out or confirm possible causes of high ESR value. You have mentioned chronic pain, fatigue, and weakness in the query. It points towards some autoimmune condition based on the medical history you gave but you need to do a few tests to confirm or rule out any ongoing autoimmune condition or disease in the body. I would suggest you the following:

1) CBC (complete blood count).

2) Autoimmune panel test including ANA (anti-nuclear antibody), RA (rheumatoid factor) factor, CRP (C-reactive protein) test.

3) Metabolic panel test including blood sugar(HbA1c), LDL (low-density lipoprotein), HDL (high-density lipoprotein), total cholesterol, triglyceride.

Please do follow up and mention relevant medical history if any in the reply to guide you further and better.

Thanks and regards.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Basuki Nath Bhagat
Dr. Basuki Nath Bhagat

Family Physician

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