Q. I did HIV RNA PCR quantitative test at 69 days, which was negative. Am I risk-free?

Answered by
Dr. Ramchandra Lamba
and medically reviewed by Dr. Sneha Kannan
This is a premium question & answer published on May 07, 2020
Hi Doctor,
I had done antibody for HIV1 &2 Rapid Screening Test at 63 days which was negative and then I did HIV RNA Realtime PCR Quantitative test at 69 days which was also negative “Target Not Detected”. I heard PCR is very sensitive and conclusive. Is that true at 70 days as well? Should I be concerned or am I risk free? Although I am having diarrea from a few days.
Thank you  

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Dr. Ramchandra Lamba

Psychiatry Psychologist/ Counsellor Sexology

Hi welcome to icliniq.

As the test are negative at 69 days , so you are free from HIV infection and need not to repeat the test. PCR test is usually not used routinely . Antigen antibody test can detect almost all cases after 4 weeks.

If you can tell me about thest rapid test for HIV 1and 2 you have done then I can give more detail ? which generation test you have tested, was it 4th generation test ?

4th generation test can pick up more than 95 percent case at 4 weeks , and you have tested after 69 days and the results are negative. So just relax. Thanks and regards.

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Thank you doctor. I did from a Lab, I am not sure which generation they use. Is RNA PCR not accurate at 10 weeks? Thanks

Dr. Ramchandra Lamba

Psychiatry Psychologist/ Counsellor Sexology
# welcome back.
The test is only antibody test and not the antigen antibody test. The antigen antibody combo test is more sensitive test .

The PCR RNA test is for viral load. As your test is negative at 69 days, so you need not to worry.

As all these are negative, so just relax.

Thanks and regards.

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