HomeAnswersSexologyhiv testingWhy is my HIV reference range close to borderline?

My HIV reference range is close to borderline. Is there a chance of acquiring HIV?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Answered by

Dr. Ashok Kumar

Medically reviewed by

Dr. Vinodhini J.

Published At December 2, 2020
Reviewed AtDecember 2, 2020

Patient's Query

Hello doctor,

I want to know why my HIV test reference range is at a close borderline. i.e. 0.89. Is there any chance of getting HIV? I have tested this now, and my window period is over a year. Please clarify my doubt. I have tested HIV by rapid kits like tridot so many times after the window period. It came back negative. But this test came negative with borderline value. Please clarify. I am very much tensed. Is there a chance of increasing values day by day? Please help.

Answered by Dr. Ashok Kumar

Hello,

Welcome to icliniq.com.

I read your query and understand your concerns.

First of all, I like to assure you that test is non-reactive rather than borderline, which means that you have no active infection. Since almost one year crossed after the exposure (I assume your one year reference of window period is about exposure), there is no chance that the test will turn positive after such a long period.

With fourth-generation tests, three months is more than enough to get tested and confirmed about HIV status. As per the available data, there is no chance that your test will turn positive in the future due to stated exposure.

I hope this helps.

Patient's Query

Thank you doctor,

But why the values came near to the border (almost borderline)? Please clarify.

Answered by Dr. Ashok Kumar

Hello,

Welcome back to icliniq.com.

The biological reference interval, which is mentioned in your report, is calculated automatically based on calibrators used during the testing process. The calibrators for the HIV duo test includes both antigen and antibody-based.

This test's cut-off value is determined based on the use of old reagents as the possible cause for borderline status.

I also like to inform you that these scores vary from laboratory to laboratory, and the level below 1.0 is non-reactive. I think the laboratory has dealt with extra caution by showing the three ranges (reactive, borderline, reactive).

We also need to understand that there is no test that is 100 % accurate. Suppose the tests come out consistently negative (sensitivity 99.9 % for HIV duo after three months of exposure) over a year. In that case, we need to look for the positive side of life rather than ruminating on the same fear.

I hope this helps.

Patient's Query

is there any chance of border line values to become positive in another test?
Answered by Dr. Ashok Kumar
Dear Karthik, Thanks for follow up and asking for further clarification. As per the available data there is almost nil chance of getting HIV positive result in future from the exposure which occurred about one year back. In other words the chances of becoming borderline test to reactive for HIV is nil on the current date and in future. The borderline test result is often due to laboratory problems and do not reflect your risk of HIV in future from the exposure of one year. So it can be said that there is no chance of getting reactive test result due to current borderline test result. I hope this answers you. Feel free to write back to me if you have more questions. Thanks and regards.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Ashok Kumar
Dr. Ashok Kumar

Geriatrics

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