Q. Should I be concerned if my HIV results on the 90th and 188th day of exposure are negative?

Answered by
Dr. Ravinder K. Sachdeva
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Jun 11, 2021

Hi doctor, I have attached my HIV reports taken on the 90th and 188th day after exposure for your reference. Both the reports are negative. There was no further exposure. Should I be concerned?



Welcome to

I have gone through your reports (attachments removed to protect the patient's identity). Your test results will be considered conclusively negative if there is no further exposure. I hope my answer helps in relieving your stress. Please do not hesitate to ask if there is any further question.

Best wishes.

Hi doctor,

Thanks for the reply.

I am worried about the window period. The exposure took place two years ago. And each month after that, I have tested, so after 89 days of exposure, also I have tested. Next test I did after 187 days of exposure. All tests were negative. They were CMIA 4th generation combo tests. And there was no further exposure. So I want to ask whether I have tested at the right time or during the window period we calculate for the 4th generation CMIA test? I am so much stressed for four days. I cannot sleep. I hope your answer will help me move on in my life.



Welcome back to

1) Window period is the period of exposure to the laboratory detection of the antigen.

2) The test kits used to diagnose HIV (human immunodeficiency virus) are highly sensitive and specific and unlikely to miss the infection.

3) The recommendations are to get tested at three to four weeks of last exposure by HIV 4th generation rapid test. If the result is negative, get a confirmatory HIV rapid antibody test at three months of previous exposure. There is no need to repeat the test further if there is no more exposure.

4) Although not in testing recommendations, HIV RNA PCR (polymerase chain reaction) (qualitative) gives another sense of security. But this is an expensive test and needs to be done from an accredited lab. Therefore, I re-emphasize that this test is not in the recommendations.

5) In your case, the nature of exposure, whether vaginal, anal, oral, unprotected, or protected, has not been described, but believing your test results, as mentioned by you, these will be considered conclusive if there is no further exposure.

6) You can surely relax and move forward based on these results.

7) If you have any specific symptoms or complaints, I can advise accordingly. In addition, getting tests for other STIs (sexually transmitted infections) like hepatitis B and C, VDRL (venereal disease research laboratory tests), herpes simplex 1 and 2 is also advisable, as these share a common route of acquisition.

8) I hope these facts alleviate your stress and anxiety, but please revert if there is any existing doubt.

Best wishes.

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