Does Hodgkin's lymphoma cause elevated CD3 and CD57 NK cells?

Question

Hello doctor,

I recently tested positive for Lyme disease. I have a history of stage IIA lymphoma, 15 years ago, and I am in full remission ever since. My reports, that I have attached, show elevated CD3 and CD57 NK cells. The lab recommended that an oncologist looks at this for a possible Hodgkin's connection. Could this be a recurrence of cancer? Or is this a sign of cancer that was in my body before? What do you recommend?

Answer 1

Hello,

Welcome to icliniq.com.

I have seen your reports (attachment removed to protect patient identity).

Lyme disease is usually associated with decreased CD57, especially in the chronic form.

But, the lab findings reveal a high CD57. It also reveals high CD3 levels. Both high CD57 and CD3 levels can be linked to rheumatoid arthritis.

But on the other hand, the test results are negative for Borrelia LFA-1, which is associated with rheumatoid arthritis.

I suggest that you complete the course of treatment for Lyme disease and then repeat the tests again.

For further queries consult an internal medicine physician online --> https://www.icliniq.com/ask-a-doctor-online/internal-medicine-physician

Answer 2

Hello,

Welcome back to icliniq.com.

Abnormalities in levels of CD3 and CD57 are not associated with Hodgkin's lymphoma.

On the other hand, they are possibly connected with chronic infections and autoimmune diseases.

For more information consult an internal medicine physician online --> https://www.icliniq.com/ask-a-doctor-online/internal-medicine-physician

Answer 3

Hello,

Welcome back to icliniq.com.

The MCH (mean corpuscular hemoglobin) and MCV (mean corpuscular volume) values are low, indicating microcytic hypochromic anemia. It is mostly an iron-deficiency anemia, as your hemoglobin level and hematocrit levels are within normal range.

It can be due to the presence of inflammation which is consistent with Lyme infection that you have.

Low neutrophils and high lymphocytes count can also be due to the presence of an infection.

For more information consult an internal medicine physician online --> https://www.icliniq.com/ask-a-doctor-online/internal-medicine-physician

Answer 4

Hi,

Welcome back to icliniq.com.

No, it cannot be leukemia.

To diagnose leukemia, there must be blast cells (leukemia cells) in the complete blood count. Blast cells are not found in your complete blood count, which excludes leukemia.

For further queries consult an internal medicine physician online --> https://www.icliniq.com/ask-a-doctor-online/internal-medicine-physician

Does Hodgkin's lymphoma cause elevated CD3 and CD57 NK cells?

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