HomeAnswersInternal Medicineweight lossWhy do I struggle much to lose weight?

Why am I not losing weight in spite of exercise and diet?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

Dr. K. Shobana

Published At October 8, 2016
Reviewed AtFebruary 6, 2024

Patient's Query

Hi doctor,

I could not lose weight no matter what I do. I have acne on my chin and cheeks, increased facial hair and my hips, thighs and stomach will not lean out both with exercise and diet. I was told to take Nature-Thyroid for low T3, but felt like my throat swollen up when I take it. It would make me feel short of breath. So, I have to get off that and I just feel like this is hopeless. I am honestly tired of killing myself in the gym and eating ridiculously healthy and only seeing the scale go up. Please help.

Answered by Dr. Sadaf Mustafa

Hello,

Welcome to icliniq.com. Firstly, I want to assure you to take a deep breath and remain calm. To better understand your situation, could you please provide some important details? Have you been diagnosed with PCOS (polycystic ovarian syndrome), as it could be a factor contributing to hormonal imbalances? Additionally, what is your TSH level, and do you experience constipation, cold intolerance, or any hair and nail issues? Have you been screened for hypertension and diabetes? If your BMI is not accurately 32.6, kindly provide your height and weight. Has the weight gain been recent, and did it coincide with starting the gym, supplements, or hormones? Could you describe your gym routine, including the number of days you go and the duration of each session? Furthermore, it would be helpful to get an outline of your meals, including breakfast, lunch, and dinner, as well as whether you consume snacks and what they typically consist of. Lastly, an estimation of your daily calorie intake in 24 hours would be beneficial for further assessment. Thank you for providing this information; it will assist in better understanding your situation and finding appropriate solutions.

Patient's Query

Thank you doctor,

I was diagnosed by a bio-identical hormone specialist with low progesterone. I was put on 140 mg of progesterone. I took it for about two years and lost a lot of weight. I got down to about 147 pounds. No, the BMI is no longer accurate. I am now 165 pounds. I have attached my recent blood work. My TSH was normal. No, I have been going to the gym for six to seven days a week and working out cardio and weights. I pack my own meals daily with no salt and sugar. I eat mainly chicken and some sort of vegetables. I do not eat pasta or bread. I have not had bread for about four years now. I just know something is wrong. I eat under 1200 calories and I know that with the way I live, I should be really lean and not what I am now.

Answered by Dr. Sadaf Mustafa

Hello,

Welcome back to icliniq.com. Thank you for providing me with information, here is what I am thinking. We have to rule out medical causes of hirsutism (increased facial and chin hairs), that is our lead. Usually, we classify by the presence or absence of menstrual irregularities. I am not sure how your cycles are since you have started taking the hormones. Based on the marginally elevated serum total testosterone, along with other potential features such as obesity, difficulty in losing weight, and hirsutism, PCOS could be a possible diagnosis. To confirm this, an ultrasound of the ovaries would be helpful. However, other conditions like Cushing's syndrome, hyperprolactinemia, congenital adrenal hyperplasia, and 21-OH deficiency should also be ruled out before proceeding further. Additional blood work is needed, including early morning serum free testosterone, prolactin level, cortisol level, DHEA-S (dehydroepiandrosterone), and 17-hydroxyprogesterone levels. Keep in mind that gaining muscle mass can contribute to weight, and checking body fat may reveal a positive change. The need for T3 supplements and progesterone supplementation should be re-evaluated. Progesterone levels can fluctuate during the menstrual cycle, so timing matters for accurate assessment. Feel free to share any concerns, as this is not the final diagnosis, and I want you to understand the potential causes of hirsutism and weight gain and the appropriate steps to be taken. If you have the mentioned blood work and ultrasound or CAT scan results, please provide them for further evaluation.

Patient's Query

Thank you doctor,

I get regular periods in every 28 to 30 days. I never missed a period till date. I also have frequent lightheadedness and headaches. I am going to visit an endocrinologist next week. Shall I ask her to conduct the tests you mentioned before?

Answered by Dr. Sadaf Mustafa

Hello,

Welcome back to icliniq.com. Yes, she should know to order these investigations. I would also suggest getting FSH (follicle stimulating hormone), LH (luteinizing hormone), estrogen and progesterone levels. Are you still taking estrogen or progesterone supplements?

Patient's Query

Hi doctor,

No, I am not taking any medicine now. Do you know what could be causing the dizziness and the belly problem?

Answered by Dr. Sadaf Mustafa

Hello,

Welcome back to icliniq.com. The dizziness you are experiencing could have several underlying causes, including orthostasis, which refers to your body's inability to quickly adapt to changes in position, leading to dizziness when changing posture abruptly. It's essential to understand if you feel dizzy only when you change positions or if it persists even when lying down. Additionally, observe if you experience dizziness during workouts and whether it occurs before or after exercising. Regarding the fat on your belly, it could indeed be related to the endocrinological disorders mentioned earlier, such as Cushing's syndrome and PCOS. To gain a more comprehensive understanding, it is necessary to consider other symptoms such as abdominal pain, nausea, vomiting, or diarrhea. Evaluating all these factors will aid in the proper diagnosis and management of your condition.

Patient's Query

Thank you doctor,

I get dizzy when I lay down and mostly when I am lying down. I have diarrhea, but no other abdominal discomfort. It is just my belly bloats at any time I eat food almost like I am pregnant. It feels like my whole body is swollen from my belly down. I just feel big like I cannot get the weight off no matter what I do. Do you have an idea what this could be?

Answered by Dr. Sadaf Mustafa

Hi,

Welcome back to icliniq.com. Considering the symptoms and the situation, PCOS does seem to be a likely possibility. Diarrhea can indeed cause dizziness, especially if multiple episodes occur in a day. It would be beneficial to note if there is any association between the diarrhea and specific foods or milk consumption. Adequate hydration is crucial, so please share how much water you typically drink in 24 hours. Additionally, it is essential to know if you use any weight loss or protein supplements as part of your routine. Gaining a comprehensive understanding of these factors will assist in determining the appropriate course of action and management for your condition.

Patient's Query

Thank you doctor,

No, it is not that often and just like once in the morning. I drink a lot of water and I pee a lot at night. I go around 12 times in the middle of the night. It is exhausting. Yes, I cannot eat bread or anything with dairy and it really hurts my stomach. Will treatment for PCOS make it easier for me to lose weight? I have got an ultrasound earlier and there were no cysts.

Answered by Dr. Sadaf Mustafa

Hello,

Welcome to icliniq.com. Thank you for providing further information. With the new details of excessive urination, difficulty tolerating dairy, and a negative ultrasound for cysts, it indeed suggests a potential change in the diagnosis. Have you ever tried a gluten-free diet, and if so, were you able to tolerate it well? Additionally, do you notice that your urine color appears very white or transparent rather than having a normal lime color? Regarding PCOS, I initially considered it due to your mentioned symptoms like facial and chin hairs, central obesity, elevated testosterone, and progesterone deficiency. To confirm the diagnosis, a pelvic ultrasound is typically conducted to check for the classic "pearl in string" appearance associated with PCOS. I would like to know when you had the ultrasound, and were the testosterone and progesterone levels obtained at the same time as the other tests? If PCOS is confirmed, the treatment approach is usually straightforward. For female patients seeking pregnancy, Metformin may be tried, while hormone replacement is an option for those who do not wish to conceive. Accurate diagnosis and proper treatment are crucial, and I'll be here to assist you throughout the process.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Sadaf Mustafa
Dr. Sadaf Mustafa

Internal Medicine

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