Q. How to manage a reddish swollen knee due to an insect bite?

Answered by
Dr. Basuki Nath Bhagat
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Aug 31, 2022

Hello doctor,

My wife was bitten behind her knee, probably by an insect (we did not see what it was) in the house. We have recently moved to this place, so I am not sure what it could be. After the incident in the evening, the area behind her knee was swollen. By the following day, it had expanded, so we went to a pharmacy, and they gave her Cortisone cream. The cream fixed the swollen area pretty quickly. But it seems it is traveling to the bottom, and today is the second day that her ankle is swollen and her calf a little bit. The original area is red and slightly bruised, but that is not expanded and has turned pale over the days. Kindly help.

Thank you.



Welcome to

I have read your query and understand your concern. I saw the attached files (attachments removed to protect the patient's identity). My findings are the following.

1. I can see a pale area behind the knee and swollen ankle in comparison to the right ankle.

2. I can see a red spot behind the knee, which could probably be a bite mark of an insect.

My questions are:

1. Is there any pain in any part of the left leg or itching behind the knee?

2. Any pain on deep palpation over the swollen ankle and any difficulty in weight bearing while walking?

Please reply to the above questions and add any other signs and symptoms (if any) to guide you more. You mentioned that she took three tablets of steroid medicine, and this incident happened five days back. The duration point toward that it is mild, and taking the non-steroidal anti-inflammatory (NSAIDs) group of medication would help to resolve the ongoing inflammation. Therefore, I would suggest you follow these measures:

(consult a specialist doctor, discuss with them, and take medications with their consent).

1. Take the following combination of medicine Paracetamol (325 mg), Aceclofenac (100 mg), and Serratiopeptidase (15 mg) of any brand available, twice a day for three to five days.

2. Take tablet Avil (Pheniramine Maleate 25 mg) before bedtime for two days only.

The swelling would also resolve with a decrease in the ongoing inflammation by taking the above medicine. Do lukewarm sponging over the swollen ankle. During night-time, keep the left lower leg elevated by keeping 2 to 3 pillows behind it.

I hope you find my reply helpful. So reply to the above questions and follow up if you have any further queries.

Thank you.

Hello doctor,

Thank you for your response.

There is no pain, even when I apply pressure to the bitten area or other swollen regions. The insect-bitten area feels a bit sore, and it also feels a bit hardened. No pain in the swollen ankle, and I have no difficulties walking. I am not sure about the possibility of getting the combination drug Paracetamol (325 mg), Aceclofenac (100 mg), and Serratiopeptidase (15 mg) without a prescription from the pharmacies here, but I will try. I will follow your instructions. Hopefully, it will get better soon.

Thank you.



Welcome back to

It is good to read that there is no sign of pain and present swelling is due to ongoing inflammation because of the insect bite. You might get the above-suggested medicine as it is a non-steroidal anti-inflammatory drug (NSAIDs) that generally do not require a prescription. If you do not get this medicine combination in your area, ask the pharmacist to give Serratiopeptidase-containing medicine.

Please follow up if necessary regarding the current query.

Thank you.

Was this answer helpful?


Same symptoms doesn’t mean you have the same problem. Consult a doctor now!

Related Questions:
What has caused this swelling on my face, insect bite or allergy?

Is that due to some allergy ...   Read full

What is causing severe allergic reaction to insect bites?

.. bites are harmless, though they feel uncomfortable and unpleasant. But some of the insect-like bee, wasp or as you mentioned sand mozzies may hurt and cause burning, swelling, pain, etc. Some peoples become allergic to such insect poison. They als...   Read full

I recently got a knee swelling. Should I rest or move around like I normally would?

.. description, the MRI reports suggest an injury. You did not mention a specific incident or accident that may have lead to a sprain of the ACL. Without a real injury, the knee swelled up again, with the stair climbing. The entire presentation point...   Read full

Also Read Answers From:

ideaComprehensive Medical Second Opinion.Submit your Case

Also Read

Impact of COVID-19 on Female Sexual Health
Women have been affected and still face the consequences of Coronavirus on their sexual health. Read more about the impa...  Read more»
Carpal Tunnel Syndrome in Pregnancy
Carpal tunnel syndrome in pregnancy occurs when a nerve supplying the hand is compressed at the forearm level due to the...  Read more»
Breaking the Link-Irritable Bowel Syndrome and Bacterial Overgrowth
A surplus of bacteria in the intestine causes irritable bowel syndrome (IBS). Read the article below to know more about ...  Read more»

Ask your health query to a doctor online?

Ask an Internal Medicine Physician Now

* guaranteed answer within 4 hours.

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.