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HomeAnswersRheumatologyjoint painWhy do I have joint pain, migraines, and knee burn at night?

Can someone have uncomfortable joint pain without arthritis?

The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

iCliniq medical review team

Published At March 26, 2023
Reviewed AtOctober 11, 2023

Patient's Query

Hello doctor,

I am a 42-year-old female. I have joint pain (both hands, knees, and neck), fatigue, migraines, depression, and sometimes a burning sensation in my knees at night. I have increased stiffness and pain in the morning and settle throughout the day and the pain resumes at night. I took an Aimovig injection two months ago. I am currently taking Atorvastatin 20 mg daily, Vitamin D3 5000 IU one daily, Wellbutrin XL 150 mg 1 daily, and Sumatriptan 25 mg if needed. X-rays were taken and they were negative for arthritis. I consulted a rheumatologist and he told me that he was sure that I did not have arthritis. I asked him why would a 42-year-old have joint pain and he answered that it happens. Is this true, can someone suffer uncomfortable joint pain without having arthritis? If so are there any other explanations for the joint pain?


Welcome to icliniq.com.

I have read your query and understand your concern. Yes, you are right, you may have joint pain without arthritis. There could be a few reasons for your joint pain.

1. Side effect of Atorvastatin.

2. Chronic fatigue syndrome

3. Due to Aimovig (Erenumab) injection.

Please do the following laboratory tests and follow up.

1. ESR (erythrocyte sedimentation rate).

2. CRP (C-reactive protein).

3. ANTI-CCP (anti-cyclic citrullinated peptide) antibody.

4. ANA (antinuclear antibodies).

5. Vitamin D levels.

Thank you.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. K. Shanmuganandan
Dr. K. Shanmuganandan


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