HomeAnswersHematologykell antigenWhat are the risks to surrogate if the male donor is Kell positive?

Male donor is Kell positive. What are the associated risks to the surrogate?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Answered by

Dr. Kamal Kant Sahu

Medically reviewed by

Dr. Divya Banu M

Published At April 29, 2019
Reviewed AtAugust 22, 2023

Patient's Query

Hello doctor,

My husband and I will be using a surrogate to have kids. My husband is Kell-positive (heterozygous). What are the risks to this that the surrogate would need to be aware of?

Hello,

Welcome to icliniq.com.

A few points include:

1. As per medical facts, the first pregnancy remains silent. In your case, the surrogate is Kell negative which means her body is still not exposed to Kell antigens which is good, so this pregnancy will be safe.

2. As the husband is heterozygous, it means he has only a 50 % chance of having a baby Kell positive. In the rest 50 %, there is no risk of complications.

So, theoretically, this pregnancy should go silent without complications. But then the surrogate will be exposed to Kell antigen from your husband, she should be aware of this risk which can create trouble in future pregnancies if the male is Kell positive.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Kamal Kant Sahu

Dr. Kamal Kant Sahu

Hematology

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