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Q. What can be the cause of prolonged macrocytosis?

Answered by
Dr. Parth R Goswami
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Sep 21, 2017

Hello doctor,

I have had macrocytosis for a long time. My last B12 and folate levels were high. I have symptoms of nervousness, snarkiness, light headedness, palpitations, and sometimes tingling in the hands and feet. It is making me crazy. My MCV is 104.9, MCH 35.6 and last TSH 2.18. I have consulted many doctors but they do not think there is a problem. Can you help?

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Hello,

Welcome to icliniq.com.

  • Macrocytosis can be present because of hypothyroidism, alcohol, liver disease, etc. Your TSH value is within the limit. So, I do not think a thyroid problem can be the cause.
  • You can get the following tests to rule out liver and kidney problem:
  1. SGOT (serum glutamic oxaloacetic transaminase)
  2. SGPT (serum glutamic pyruvic transaminase)
  3. Serum urea.
  4. Creatinine.
  • For palpitation, investigate with EKG (electrocardiogram). Check your calcium level also.
  • If needed, further work up can be done with NCV (nerve conduction velocity) or EMG (electromyography) investigation.
  • If no significant cause is found, then a history of stress and anxiety should be ruled out, which can lead to a headache with palpitation. Consult a neurologist if needed, for an examination and discuss your case.

Take care. Hope this information will help you.

For more information consult a hematologist online --> https://icliniq.com./ask-a-doctor-online/hematologist


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