Should I do a bone marrow aspiration to find out why my WBC count is low?

Q. What could be the reason for the low WBC count in an otherwise healthy female?

Answered by
Dr. Goswami Parth Rajendragiri
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Feb 10, 2023 and last reviewed on: Jun 06, 2023

Hi doctor,

I am 40-year-old female with no symptoms, and in good physical condition. I typically have a blood test every year. I discovered that I had mild leucopenia at 3900/mm since the start of the year, but recently, my blood test has come back at 3600/mm. My differential counts are within the normal range. My hemoglobin is 12.7 g/dL, and I have mild Sjogren's syndrome, for which my doctor has said that no treatment is necessary. Due to inadequate ovarian reserve, I have no children, and my globulin is significantly higher (4.6 g/dl) on the LFT report. Due to subclinical hypothyroidism, I have been taking Thyronorm 50 mcg since last year. So my inquiry is, what comes next? My WBC is low; why? Do I need to rule anything with bone marrow aspirations?



Welcome to the,

You are having Sjogren's syndrome as per mentioned history.

Your leukocyte count is mildly low, which might be due to Sjogren's syndrome. Your peripheral smear examination report is normal and hemoglobin level and platelet count are also within limit.

So according to my opinion, there is no need for bone marrow aspiration study. So no need for further workup.

If dry mouth, joint pain, muscle pain and dry eye symptoms are troublesome then you can consult a rheumatologist for detailed evaluation and management.

I hope I have answered your question.

Let me know if I can assist you further.


Was this answer helpful?


Same symptoms doesn’t mean you have the same problem. Consult a doctor now!

Related Questions:
My little child has fever and low WBC count. Can it be dengue fever?

Hello doctor,My 3 years and 6 months old daughter has been suffering from a fever of about 100 to 102 for the past three days ... This can happen in a viral fever also ...   Read full

I am concerned about Sjogren's syndrome due to dry eyes and mouth. Kindly interpret my blood report.

However, I had reported mild dry mouth and mild dry eyes ... My eye doctor confirmed via tests that I do have mild dry   Read full

My blood report shows low WBC count. Is this an serious issue?

.. have read all three reports (attachment removed to protect patient identity). The total WBC (white blood cells) count is low only in the latest attached report. There are many causes for low WBC count, including viral infection to blood cancer.   Read full

Also Read Answers From:

ideaComprehensive Medical Second Opinion.Submit your Case

Also Read

PCOS and Liver Problems
The hormonal imbalances in polycystic ovary syndrome could cause liver diseases. Read the article to know the relationship between these medical conditions.  Read more»
Inferior Alveolar Nerve Lateralization Technique
The inferior alveolar nerve lateralization technique is a surgical lateralization technique to reposition the nerve. Read the article to know more about this.  Read more»
COVID-19 and Ebola: Similarities and Differences
This article gives a comparison and broader overview of the outbreak of the two deadliest diseases that showed a greater incidence over the last two decades.  Read more»

Ask your health query to a doctor online?

Ask a Hematologist Now

* guaranteed answer within 4 hours.

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.