I have few enlarged lymph nodes on both sides of my groin. Does it indicate lymphoma?

Hello,

Welcome to icliniq.com.

I can understand your level of confusion about transformed lymphocytes. Transformed lymphocyte means enlarged lymphocyte nucleus and prominent nucleoli. So, it will resemble a blast or malignant lymphocyte-like cell. But transformed lymphocytes do not always mean lymphoma.

However, as your FNAC (fine needle aspiration cytology) workup is not conclusive and the material was less in FNAC, you need to investigate further with histopathology of biopsy of enlarged lymph nodes.

Biopsy should be taken from enlarged nodes, and histopathology can be done from that. Histopathology or flow cytometry, like higher investigation, will rule out lymphoma conclusively. So, it would help if you investigated with histopathology or flow cytometry from the biopsy.

Discuss with your doctor about histopathology if your doctor feels so after your physical examination as your attached report is not conclusive.

I hope I have answered your question. Let me know if I can assist you further.

Best Regards.

Hello,

Welcome back to icliniq.com.

Transformed lymphocytes can be seen in reactive lymphadenitis as well. So transformed lymphocyte is not conclusive of either lymphoma or reactive lymphadenitis.

I think you should investigate further with biopsy for histopathology examination or flow cytometry as per my opinion.

I hope I have answered your question.

Let me know if I can assist you further.

Best Regards.

Hi,

Welcome back to icliniq.com.

I have seen your attached histopathology report (attachments removed to protect the patient's identity). In the report, it is written that histopathology is suggestive of reactive lymphadenitis. So, do not worry about lymphoma. Histopathology report clearly states that it is reactive lymphadenitis. Hence, now you can exclude lymphoma. It is a reactive non-specific enlarged node probably. Doctor has not written microscopic findings because there is no presence of any abnormal cells probably. Discuss all these with your treating surgeon or physician. I hope I have answered your question.

Let me know if you have more questions in mind.

Best regards.

Hi,

Welcome back to icliniq.com.

Following is my opinion on your questions. Also, the attached image is not clear (attachments removed to protect the patient's identity). So if possible, please resend the image in follow-up.

1. As per mentioned history, it could be post-surgical inflammation in that area.
2. The drained fluid could have accumulated in that area due to trauma-induced inflammation, which is seen commonly.
3. Sometimes it can take up to 15 days for complete resolution.
4. I suggest you continue to take your anti-inflammatory medicine regularly and avoid water contact in that area.
5. You can clean the groin area with normal saline.
6. If any pus comes out in the future, then bacterial infection could be possible for which topical Neosporin cream can be applied.

I hope I have answered your questions.

Let me know if I can assist you further.

Best regards.

Hello,

Welcome back to icliniq.com.

Following is my opinion on the questions you have asked.

1. In the first attached report, an enlarged lymph node is seen and they mentioned it as a reactive node. The other USG (ultrasonography) report, probably the one after the surgery shows cystic lesion. Therefore, now your swelling could be either an enlarged node or chronic inflammation-induced hard lesion.
2. The FNAC (fine needle aspiration cytology) report shows only blood which can be possible if the lesion is vascular and hard.
3. The FNAC did not report if cellular material is present or not, and shows only blood. The biopsy can be conclusive in that manner.
4. If your lesion is painful and causing discomfort then it is better to get it removed. After removal, it can be sent for a histopathology examination.
5. In the groin, reactive node enlargement is more common. It does not seem to be cancer.
6. Chronic inflammation and infection are other causes of enlarged nodes.

Hope I have answered your question.

Let me know if I can assist you further.

Best regards.

Hello,

Welcome back to icliniq.com.

The following is my further opinion on your questions.

Lymph node without fatty hilum suggests some pathology but it does not always mean cancer.

According to the attached reports (attachments removed to protect the patient's identity), FNAC was done so it is fine-needle aspiration cytology, not biopsy.

In the FNAC procedure, the needle is passed into the tissue and the material is aspirated. However, in FNAC it is possible not to get enough material sometimes.

It is showing only blood that suggests cellular material was not aspirated so, whenever blood is aspirated in FNAC, reporting is not possible.

I suggest you better get both the nodes removed and their histopathology examination should be done.

Without examination and histopathology report, it is difficult to diagnose the etiology of enlarged nodes.

Hope this information will be helpful to you while discussing it with your doctor.

Let me know if you have more questions in mind.

Best regards.