Common "Thalassemia" queries answered by top doctors | iCliniq

Thalassemia

Thalassemia is a blood disorder where the body produces an abnormal form of hemoglobin. It is an inherited disorder and is caused by either genetic mutation or deletion of some gene fragments. The symptoms are bone deformities, dark urine, tiredness, pale and yellowish skin, and poor or delayed growth.

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What causes headache in a child with thalassemia major?

Query: Hi doctor, My son is thalassemia major subject. His age is 6 months (male boy). His weight is 11.02 lbs. He is suffering from headache and fever every now and then. Some times heart beet is fast. His liver and spleen are enlarged. He has been blood transfusion in one time in last week. Now he is tak...  Read Full »


Dr. Preeti Puranik

Answer: Hi, Welcome to icliniq.com. He is suffering from thalassemia major. Here there is destruction of the blood cells due to which hemoglobin becomes low frequently. Hence he will need blood transfusions regularly. He is prone for infections because of low hemoglobin which can also cause fast heartbeat...  Read Full »

Kindly advise on the premarital health check-up done here.

Query: Hello doctor, Please provide second advice on reports. I would like to know if any other tests I should undergo apart from the existing ones.  Read Full »


Dr. Atishay Bukharia

Answer: Hello, Welcome to icliniq.com. I have gone through your reports. Please share your history or complaints. Regards.   Read Full »

Is my friend's beta thalassemia screening test seem normal?

Query: Hello doctor,My cousin of 30 years old got tested for beta thalassemia screening test. He got the result as hemoglobin A2 is 2.8 %, hemoglobin F is 0.2 %, and hemoglobin C, D, and S are not detected. Is this normal or has any complications?Please guide.  Read Full »


Dr. Prakash. H. M.

Answer: Hi, Welcome to icliniq.com. Based on your query, my opinion is as follows: The beta-thalassemia screening test appears to be normal. HbA2 levels (hemoglobin A2) are normally between 2 to 3.3% and HbF levels (fetal hemoglobin) are 0.1 to 1.2% for this age. Both are normal. The other hemoglobin typ...  Read Full »

My son has thalassemia major. Please suggest.

Query: Hello doctor, My son is 15 months old and has been diagnosed with thalassemia major. My only question is when he would require his first blood transfusion? Because typically people feel strong symptoms of anemia and need medical help when Hb goes below 6. But, my child has Hb of 3.7 probably for ove...  Read Full »


Dr. Deepak Patel

Answer: Hi, Welcome to icliniq.com. I can understand your concerns. The definite management of thalassemia is bone marrow transplant. For this HLA - human leukocyte antigen) matching is done and if possible this is the best treatment available right now. The second one is a regular blood transfusion. We us...  Read Full »

I am a thalassemia major patient with HCV. How long can I live?

Query: Hello doctor, I am a thalassemia major individual with factor XIII deficiency, HCV+. I transfuse platelet or FFP daily and transfuse RCC weekly. All these things are reacting in my body. My ferritin level is 15000 after chelation therapy. This also has a bad effect every time. I am 28 years old. How...  Read Full »


Dr. Prakash. H. M.

Answer: Hi, Welcome to icliniq.com. Your health is our concern. Based on your query, my opinion is as follows: A serum ferritin level of 15000 is too high. Along with HCV, the prognosis is somewhat poor. However, without knowing the amount of iron deposition in tissues like the liver, heart, and so on, ...  Read Full »

Can the same blood group cause problems after marriage?

Query: Hello doctor, My wife's and mine blood groups are the same. Both of our blood group is B. Will there be any problem in our married life?  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to icliniq.com. There are two major blood group systems. ABO - According to this system, the blood group can be A, B, O, or AB. Rh system - According to this system, the blood group can be Rh positive or negative. You have not mentioned the Rh grouping. You both have the same blo...  Read Full »

Do my reports show thalassemia minor positive?

Query: Hi doctor, Could you please go through my reports and tell me if I have thalassemia minor? I have attached my electrophoresis test reports. Some of the values in the report are HbF - 0.8 %, Hb adult - 66.0 %, HbA2 - 30.8 % and other non-specific - 2.4 %.  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to icliniq.com. According to the report attached (attachment removed to protect patient identity), the Mentzer index is not below 13. Usually, in thalassemia, it is below 13. Hb A2 (hemoglobin A2) level is raised, which is seen in beta-thalassemia minor as well as in hemoglobin E hemo...  Read Full »

I want to reduce my ferritin levels. Please help.

Query: Hi doctor, My ferritin level is 1500, and I want to bring it down to 150. How much will one DFO IV session or each Exjade pill reduce the ferritin level on an average? I am a healthy individual, and I do not have HIV, HCC, or any other disease.  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to icliniq.com. Your serum ferritin is high, so the cause should be found out first. It can be hemochromatosis, in which excess iron is stored in the bone marrow. Deferoxamine is used for increased iron storage in thalassemia patient. For high ferritin, phlebotomy is also...  Read Full »

What are the consequences of marrying a thalassemia minor patient?

Query: Hello doctor, My sister's partner is a Thalassemia patient. I would like to know if my sister marries him what will be the consequences? Will my sister suffer from that disease, or will it affect her child in the future?  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to icliniq.com. I can understand your concern and will solve all your doubts. In the attached report (attachment removed to protect patient identity), that guy suggests thalassemia minor. You need to investigate for thalassemia for your sister as well. Kindly investigate wi...  Read Full »

Can thalassemia minor be inherited?

Query: Hi doctor,My girlfriend has a thalassemia minor trait and I am a healthy individual person. If I get married to my girlfriend, is there a risk of this trait for my future children? Please give me some advice. Thanks a lot.  Read Full »


Dr. Prakash. H. M.

Answer: Hi, Welcome to icliniq.com. Based on your query, my opinion is as follows: Thalassemia inheritance is autosomal chromosome related. In thalassemia minor, one gene is affected. There is a 50% risk in the next generation of having thalassemia minor, as you are completely normal. Chromosomal anal...  Read Full »

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