Common "Anisopoikilocytosis" queries answered by top doctors | iCliniq

Anisopoikilocytosis

It is the condition in which the red blood cells have different size and shapes. It occurs due to underlying conditions such as anemia, thalassemia, vitamin B 12 deficiency, and folate deficiency. It is treated by treating underlying conditions using blood transfusion methods and bone marrow transplants.

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What does my CBC, and RBC anisopoikilocytosis indicate?

Query: Hello doctor, This is my CBC report and everything is normal except RBC. In it, RBC shows anisopoikilocytosis predominantly microcytic hypochromic cells along with normocytic hypochromic cells and few targets cells. WBC is within normal limits. Platelets: adequate. (MCV) mean corpuscular volume72.0 ...  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to icliniq.com. Your report is suggestive of microcytic hypochromic anemia. Do not worry about that. It is a treatable condition. With the recovery of hemoglobin level by tablet, your PS (peripheral smear) will be reverted to normal. It is not an alarming condition. But I suggest th...  Read Full »

I am fatigued with severe bone pain, and have abnormal smear findings. Is my cancer recurring?

Query: Hello doctor, I have a history of breast cancer for which the treatment got completed around two years back. Following are the current findings of my blood smear: Anisocytosis: +1, Poikilocytosis: +1, Polychromasia: +1, Ovalocytes: +1, And a few atypical lymphocytes. I am feeling very weak with se...  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to icliniq.com. Following is my opinion of your findings: Anisocytosis means variations in the size of red blood cells and poikilocytosis is variations in the shape of red blood cells. These two findings together with polychromasia could be because of hemolytic anemia. However, anemi...  Read Full »

My doctor is asking for a hematologist's opinion on my iron deficiency. Kindly advice.

Query: Hi doctor, I am 45 years old, and my RBC count is 3.17 million per cubic millimeters, hemoglobin is 4.5 gm/dl, and PCV is 16.9 %. WBC count, platelets, urea, uric acid, and creatinine are normal. I have taken the hemoglobin electrophoresis test also. In that Hb (adult) is 98.7 %, Hb A2 is 1.3 %. The...  Read Full »


Dr. Abdul Aziz Khan

Answer: Hi, Welcome to icliniq.com. I read your query and understand your concern. It could be iron deficiency anemia. But I need to know the cause of the iron deficiency. It would be best if you replace iron either orally or intravenously. But if you are having symptoms of anemia, then I would suggest ...  Read Full »

I have been having lethargy and breathing difficulties along with raised RDW and anisopoikilocytosis. What could be the cause?

Query: Hello doctor, I am a 23-year-old female, measuring height 62 inches and weight 115.74 pounds Lately, I have been dealing with symptoms including dizziness, lethargy, difficulty in breathing, rapid breathing during mild activities like changing bed sheets, easy fatigability, and occasional mild che...  Read Full »


Dr. Sugreev Singh

Answer: Hello, Welcome to icliniq.com. Thank you for your query. Low blood pressure and vitamin deficiencies can indeed contribute to the symptoms you are experiencing. Increasing your fluid intake, such as drinking juices, water, and lemon water, can help raise your blood pressure and improve your overall...  Read Full »

My blood smear shows mild anisopoikilocytosis. Should I be concerned?

Query: Hello doctor, I am 39 years old. I got a master health checkup done last week. In the blood report, the RBC smear shows mild anisopoikilocytosis with normochromic red cells mixed with microcytic, hypochromic red cells, and no hemoparasites. I am attaching my test report. What is the treatment for t...  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to icliniq.com. I have gone through your test report (attachment removed to protect patient identity). Your peripheral smear showing mild microcytic RBC (red blood cells) and MCV (mean corpuscular value) are slightly low, but I do not think it needs any further workup as all other sm...  Read Full »

Is anisopoikilocytosis dangerous?

Query: Hello doctor, I am a 53 year old woman diagnosed with polycythemia vera (PV) three years ago. I am being treated with phlebotomy. I have fatigue at times, as well as some thinking impairment at times. Over time I have developed various anomalies in my blood test results, which my doctor explained as...  Read Full »


Dr. Prakash. H. M.

Answer: Hi, Welcome to icliniq.com. Based on your query regarding polycythemia, my opinion is as follows: Due to nutritional deficiencies, secondary to excessive RBC (red blood cell) production and also mild dyserythropoiesis (defective development of red blood cells), you can find microcytic hypochromic ce...  Read Full »

What is the treatment for high platelets count with mild anisopoikilocytosis?

Query: Hello doctor, My wife is having high platelets count, diagnosed with mild anisopoikilocytosis, predominantly normocytic with ovalocytes (RBC), WBC mild leukocytosis is present, platelets: appear increased in the smear.  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to icliniq.com. The increased platelet count in your wife case seems to be due to reactive thrombocytosis. The iron deficiency anemia can lead to reactive thrombocytosis and so platelet count can be high. You need to treat her anemia with Ferrous Ascorbate tablet like medication for...  Read Full »

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