Common "Duloxetine" queries answered by top doctors | iCliniq

Duloxetine

Duloxetine is an antidepressant drug that belongs to the drug group selective serotonin and norepinephrine reuptake inhibitors (SSNRI). This drug is used to treat anxiety, depression, fibromyalgia, nerve pain associated with diabetes, and other chronic muscle pain. It is available in a capsule form, which has to be taken orally.

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All the answers published in this website are written by verified medical doctors, therapists and health experts. The Content has been moderated by iCliniq medical review team before publication. Post your medical clarifications on iCliniq by choosing the right specialty and get them answered. Your medical queries will be answered 24/7 by top doctors from iCliniq.

How to overcome the manic episodes caused by Cymbalta?

Query: Hello doctor, I recently was on Cymbalta minimum dose but did not feel better. I felt worse and was told to up the dose then I took 120 mg, still felt bad. So I abruptly stopped this and it triggered discontinue syndrome and hypermania. I have not felt the same since. I am not suffering so much now...  Read Full »


Dr. Aditya Gupta

Answer: Hello, Welcome to icliniq.com. Considering the history of mania (even if it is drug-induced), it is not advisable to start Effexor alone in my opinion. So, I would suggest you discuss with your treating psychiatrist regarding starting Seroquel regularly as it also acts on depressive symptoms, or...  Read Full »

I have side effects from Cymbalta. Please help.

Query: Hello doctor, I am a 55 year old healthy woman. I have had chronic depression since adolescence. I historically do well with a low dose of antidepressant. When I do not take one, it usually does not work out. I have been on a low dose of Cymbalta for the past five years. 20 mg. Lately, I have been e...  Read Full »


Dr. Nidhi Jain

Answer: Hello, Welcome to icliniq.com. Until now, how many episodes of depression did you have (episodes means at least two months of complete recovery between two episodes)? Or, is it continuous for five years? Any family history of depression?  Read Full »

How to get rid of constant lower back and neck pain?

Query: Hi doctor, I have consistent lower back and neck pain. I have been diagnosed with cervical disc herniation before 20 years and lumbar disc herniation before 12 years. An L2 nerve block procedure was done before 11 years. I did my MRI before three years.   Read Full »


Dr. Atul Prakash

Answer: Hi, Welcome to icliniq.com. MRI (magnetic resonance imaging) can show disc bulges present in both the neck and back. The degree of nerve root compromise will determine the degree of symptoms and taking conservative management helps a lot. I need to see your MRI. As your MRI was taken before three ...  Read Full »

I feel cracking sound in my joints. What could be the reason?

Query: Hi doctor,One year back, while sitting on a chair in office I felt as if my back got stuck and was unable to move. I took two painkillers and managed to sit there for a while, but after two to three hours the pain started radiating to leg. I was diagnosed with moderate disc herniation at L4 to L5 an...  Read Full »


Dr. Anshul Varshney

Answer: Hello, Welcome to icliniq.com. I have gone through your reports (attachment removed to protect patient identity), but you need to provide me the following details so that I can help you better. Is the pain radiating to the legs? Do you have any tingling or numbness in your legs? Any aggravation ...  Read Full »

I am taking Duloxetine for severe depression and anxiety. Will it worsen diarrhea related to irritable bowel syndrome?

Query: Hi doctor, I am a 41-year-old male suffering from severe anxiety, depression, fast heartbeat, excessive sweating, IBS diarrhea, and nervous weakness for the past 15 years. I have consulted multiple psychiatrists, but not many medications have suited me. Currently, my doctor has recommended Nexito Fo...  Read Full »


Dr. Vipul Chelabhai Prajapati

Answer: Hello I am glad you chose icliniq for your medical-related queries. I understand your concern. For IBS (irritable bowel syndrome) diarrhea, anxiety, and depression, Duloxetine is known to be effective. However, it may initially increase anxiety for a few days. If available in tablet form, you can ...  Read Full »

Please suggest best treatment for fibromyalgia.

Query: Hello doctor,I was diagnosed with fibromyalgia a few years ago. Over the past three years, it has gotten much worse. I take Lyrica two times a day and Tramadol as needed for the pain. I still have a great deal of pain every day. The Lyrica makes me feel like I cannot think straight and the Tramadol ...  Read Full »


Dr. Anshul Varshney

Answer: Hi, Welcome to icliniq.com. Fibromyalgia is a very frustrating condition, but with the help of the patient, a doctor can treat it. I have treated my patients with all the drugs you have mentioned by managing the doses, but I always ask my patients to do meditation that would help the most in this ...  Read Full »

Does decreased blood flow to the penis cause erectile dysfunction?

Query: Hi doctor, I am a 21-year-old male and have noticed dramatic changes in my energy levels and with my everyday life. It is hard for me to go to sleep or stay asleep. I cannot perform my job at 100 percent because my body is just so exhausted. I have had erectile dysfunction, which is affecting my ma...  Read Full »


Dr. Ankush Jairath

Answer: Hi, Welcome to icliniq.com. Please answer few questions. What kind of erectile dysfunction are you suffering from? Do you have total erectile dysfunction? Is it that you can have an erection but not enough to have penetration into the vagina? Or if erection is there enough to have penetration, but t...  Read Full »

Can Cymbalta and Phentermine be used together for weight loss?

Query: Hi doctor, I take Cymbalta 60 mg for depression and Trazodone 100 mg for sleep. Can I take Phentermine for weight loss without problems of serotonin syndrome?  Read Full »


Dr. Srivastava, Sumit

Answer: Hi, Welcome to iCliniq.com. Phentermine is a medication that is typically used for a short period of time, usually a few weeks, as an adjunctive treatment for weight reduction in patients with an initial body mass index (BMI) equal to or greater than 30 kg/m². Cymbalta, which contains the active in...  Read Full »

Will taking Duloxetine for OCD cause sexual side effects?

Query: Hi doctor, I am a 28-year-old male with a diagnosis of OCD and dissociative disorder NOS. In the last few months, I became apathetic. I think I am not depressed, but I lost interest in daily activities and hobbies. My main problem is mental rumination. I have been put on Duloxetine 60 mg hs and Mir...  Read Full »


Dr. Vishal Anilkumar Gandhi

Answer: Hi, Welcome to icliniq.com. I can understand your situation. However, Duloxetine has more sexual side effects than Escitalopram. And Duloxetine is not commonly used for OCD (obsessive-compulsive disorder). You can go with Clomipramine with Escitalopram or Fluoxetine. You should also follow the bel...  Read Full »

Can I use Paroxetine for bipolar II disorder, anxiety disorder, and agoraphobia?

Query: Hi doctor, I want to know some treatment options for my conditions. I have bipolar disorder II with social and generalized anxiety. I have panic attacks and agoraphobia due to it. Previously, I was taking Escitalopram, Venlafaxine, Fluoxetine, Sertraline, Lithium, Depakote, Quetiapine, Risperidone,...  Read Full »


Dr. Vishal Anilkumar Gandhi

Answer: Hi, Welcome to icliniq.com. You can continue taking medications that keep your condition stable at present. Duloxetine is a good option for you and it will not increase your blood pressure. Escitalopram takes around four weeks to show its full effect after starting this medication. Prozac can decr...  Read Full »

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