Common "Negative Blood Group" queries answered by top doctors | iCliniq

Negative Blood Group

The absence of Rh protein is responsible for a negative blood group in the individuals. It is less common as compared to Rh-positive blood groups. It usually causes problems during pregnancy when the mother carries Rh negative blood group and the child is Rh positive, this condition is known as Rh incompatibility.

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My pregnant wife received a positive ICT result. Please assist.

Query: Hi, My 33-year-old wife is 30 weeks pregnant. This is her second pregnancy. Her blood group is B negative, and my blood group is O positive. However, her ICT test got positive (value 1:8). She has been taking medicine for ulcerative colitis for four years (Mesalazine 2400 mg daily). She is also taki...  Read Full »


Dr. Navajith A. Mani

Answer: Hello, Welcome to icliniq.com. I read your query and understand your concern. When an Rh-negative woman reveals an indirect Coombs test (ICT) positive (more than 1:32 titer), then amniocentesis is performed, and the optical density of the amniotic fluid is determined by spectrophotometry (a sampl...  Read Full »

Is O-negative compatible with the B-positive blood group?

Query: Hello doctor, I am planning to get married, but I want to check blood group compatibility with my partner to avoid further pregnancy-related complications. My blood group is O negative, and my partner's blood group is B positive. Please suggest something.  Read Full »


Dr. Richa Agarwal

Answer: Hello, Welcome to icliniq.com. I can understand your concern. They are not compatible blood groups, so you might have difficulty conceiving because the chances of miscarriage are high. I suggest you take an Anti-D immunoglobulin injection to prevent the complications (consult a specialist doctor, ta...  Read Full »

Could my negative blood group cause any pregnancy complication?

Query: Hello doctor, I am 3 months pregnant. My blood group is O negative. Will I face any complication during pregnancy due to my negative blood group? I consulted with my doctor, and she told me to take Fertigyn 5000 injection once a week for four weeks. Is it safe? Will it make me get a normal delivery ...  Read Full »


Dr. Aishwarya Parthasarathy

Answer: Hi, Welcome to icliniq.com. When there is a negative blood group, there will be attacking agents for positive blood group in your blood called antibodies. In case your partner is positive, then there are chances of your baby being positive. The first child usually escapes, and in the case of the se...  Read Full »

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