Common "Quitting Antidepressant" queries answered by top doctors | iCliniq

Quitting Antidepressant

Abrupt quitting of long-term antidepressants causes withdrawal symptoms. They are also known as antidepressant discontinuation syndrome. Symptoms include irritability, nausea, anxiety, dizziness, insomnia, headache, tiredness, chills, rebound depression, fatigue, nightmares, etc. Consulting the physician before stopping any antidepressants is necessary as they gradually taper and reduce the dose or switch to an alternative drug to avoid withdrawal symptoms.

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I daily take Pristiq antidepressant tablet 50 mg, when can I take 5-HTP after stopping Pristiq?

Query: Hello doctor, I daily take Pristiq antidepressant tablet 50 mg, which doctor had prescribed since a year. Now I am tapering the tablet gradually as per doctor's instruction. The first week every other day and second week every two days and the third week every three days. And now this is my fourth w...  Read Full »


Dr. Vishal Anilkumar Gandhi

Answer: Hello, Welcome to icliniq.com. As you are tapering your Pristiq (Desvenlafaxine), there will be no withdrawal at all. You need to restart because of anxiety or depression disorder, not because of withdrawal. 5-HTP (Hydroxytryptophan) is not FDA approved and no guideline for it to how to use and when...  Read Full »

I missed taking Panex CR and Felicita yesterday. Please help.

Query: Hello doctor, I have been taking two medicines namely Panex CR 25 and Felicita OD since five years. From September 1st I started taking Panex CR 25 . I missed my dose of medicine for three days that is on 10th,11th and 12th. Again on 21st,22nd and 23rd, I could not take medicines. On the 26th I have...  Read Full »


Dr. Vandana Patidar

Answer: Hello Welcome to icliniq.com. Panex CR (Paroxetine) is a type of short acting SSRI (selective seretonin reuptake inhibitors). If you skip two to three doses it would cause SSRI discontinuation syndrome. You would feel the discomfort you are feeling right now. So my advise would be do not skip medi...  Read Full »

I am tapering off my antidepressant medication. Please help.

Query: Hi doctor, I am currently in the middle of a cross taper off of Gabapentin (previously at 600 milligrams, now off of it) and Lamictal (previously at 400 milligrams and now at 100 milligrams). In comparison, I continued taking 300 milligrams of Wellbutrin, which I titrated up to several days after st...  Read Full »


Dr. Vandana Patidar

Answer: Hi, Welcome to icliniq.com. Here are my opinions based on your description, which may or may not be right because to diagnose an Illness, you need details of symptoms. So, in my opinion, if Lamictal or Lamotrigine and Quetiapine helped you and now tapering, it is causing a problem. But, on the othe...  Read Full »

How can I quit taking my anti-depressants?

Query: Hello doctor, I want to quit taking my anti-depressants. Can you help me to slowly reduce doses? I am taking one Valkem of 500 and Flunil 20 mg in morning and one Valkem OD 500, Soltus 100 mg, Rivotril 0.5 mg at night.  Read Full »


Dr. Ashok Kumar

Answer: Hi, Welcome to icliniq.com. I read your query and understand your concerns about the medications. From the available details, there is a possibility that you suffered from either resistant depression or bipolar depression as some of the medications prescribed to you are often used in these conditi...  Read Full »

I am feeling stressful after I stopped taking my depression medications. Is this common?

Query: Hello doctor, I have been on depression medication since last year, I have previously had therapy for two and a half years. I stopped seeing the therapist before four months as I had been on my medicines for a few months. I felt content, and my therapist and I were leaving that school (she was an i...  Read Full »


Dr. Suresh Kumar G D

Answer: Hello, Welcome to icliniq.com. It is common to feel stressed during the freshman year and will take some months to get used to the new routine. Because of the history of clinical depression, it is advisable to consult by your doctor to review your mental state and emotional wellbeing. You can talk...  Read Full »

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