Common "Wegener's Granulomatosis" queries answered by top doctors | iCliniq

Wegener's Granulomatosis

Wegener's granulomatosis is a rare disorder that causes inflammation in the blood vessels. It mainly affects the nose, sinuses, throat, lungs, and kidneys. This results in slow blood flow to these organs. The common signs and symptoms include pus-like crusty drainage from the nose with stuffiness, sinus infections, nosebleeds, coughing with blood, fever, fatigue, and shortness of breath. The cause is unknown, and the treatment involves immunosuppressive drugs and plasma exchange (plasmapheresis).

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What does borderline positive c-ANCA levels indicate?

Query: Hello doctor,My c-ANCA levels are 5.6 U/ml (borderline positive). I have hypertension and proteinuria (3g), high serum creatinine (2.4), and UTI. My other autoimmune tests and serum electrophoresis results are negative. What should I do and what is the general prognosis?  Read Full »


Dr. Anshul Varshney

Answer: Hi, Welcome to icliniq.com. Based on your query, my opinion is as follows: C-ANCA (antineutrophil cytoplasmic antibodies) positivity indicates Wegener's Granulomatosis. In this condition, there is involvement of the upper and lower respiratory tract and kidneys. The most common diagnosis, while ki...  Read Full »

My 28-year-old wife has been diagnosed with Wegener's granulomatosis. Is this disease curable?

Query: Hello doctor, I married a girl who is 28 years old now. We got married a year ago. She was diagnosed with Wegener's granulomatosis. She is taking medications and injections. I learned about the severity of the disease, so I started feeling low. I am attaching her blood work and reports. I need to kn...  Read Full »


Dr. Ashaq Hussain Parrey

Answer: Hello, Welcome to icliniq.com. I have seen these reports (attachments removed to protect the patient's identity) in the past also. From these reports, I can say that she is in remission, which means the disease is under control. I understand your concern as the disease is lifelong, and once it is ...  Read Full »

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