HomeAnswersMedical Gastroenterologymicroscopic colitisI have microscopic colitis despite a negative biopsy. Why?

Can someone have microscopic colitis despite getting a negative biopsy report?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

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Published At April 27, 2023
Reviewed AtOctober 9, 2023

Patient's Query

Hi doctor,

I had a colonoscopy, and my doctor informed me that I had microscopic colitis. I have chronic watery diarrhea, that has lasted five months ago. I have severe left side pain, nausea, and feeling like that I am about to throw up. I also have lost 27 pounds, since two months due to these symptoms. All other diseases have been ruled out. My question is, could I still possibly have microscopic colitis, even though my biopsies were negative. Please help.

Hi,

Welcome to icliniq.com.

Thank you for your query,

Microscopic colitis is not that severe compare to other like crohn's disease or ulcerative colitis, and it does not lead to colon cancer, but it is painful and cause watery diarrhea.

Kindly follow following advice.

  1. Avoid carbonated drink, caffeine, dairy products, and fatty foods.
  2. Do not take Aspirin or analgesic medication as it make it worse.
  3. Take fiber diet.

Your query seems like it is persist, it may reoccur so follow above advice. Consult a specialist doctor,discuss with them, and take the medication with their consent.

Thank you.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Vedprakash Verma
Dr. Vedprakash Verma

General Practitioner

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