HomeAnswersNeurologymagnetic resonance imagingI underwent an MRI scan to know about my brain health. What does my report suggest?

What does an MRI scan suggest about a person's brain health?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

iCliniq medical review team

Published At May 2, 2023
Reviewed AtMarch 27, 2024

Patient's Query

Hi doctor,

I am sending you my MRI reports. Please advise about brain health.

Thanks.

Hi,

Welcome to icliniq.com.

I understand your concern.

I reviewed your reports (the attachments removed to protect the patient's identity). According to this report, a small area of insult has been seen in the midbrain. Moreover, the radiologist also has indicated some mild cerebral atrophy. This finding is only essential if you have significant memory problems.

One who experiences a stroke must be screened for controllable risk factors and start medicine that reduces re-stroke risk. In addition, it is necessary that imaging of cerebral vessels be done.

I hope this information will help.

Thanks.

Patient's Query

Hi doctor,

Thank you for the reply.

My question is that the patient does not have severe memory problems but some minor cognitive issues, such as remembering the year and month but forgetting the date. He can drive appropriately, dress, and has no gait disturbances; his strength is also good. He does sometimes get confused when writing cheques. With clock reading, he usually pauses to tell the time but gets it primarily correct. He can write and follow instructions, just some figures can be confusing, but he gets them on repeated trials. These issues have not progressed. Would a PET scan be necessary? I heard that a PET scan could give a false positive regarding stroke as it can show hypometabolism.

Thanks.

Hi,

Welcome back to icliniq.com.

I understand your concern.

Well, we always interpret one's cognitive ability based on a person's level of education and age. If the 57-year-old patient you described is literate, then your description shows that he has a cognitive problem. It does not mean he has dementia at present, but he suffers from a minimal cognitive impairment (MCI). MCI cases may improve or remain stable for a long time, but a small number may progress to dementia. In cases of MCI, screening for possible underlying diseases should be done that may affect the brain's normal function. Moreover, an EEG (electroencephalogram) is necessary to check the brain activity in the awake state. In addition, a base and then follow-ups with cognitive tests by a neurologist are required to evaluate the degree of cognitive impairment and to determine whether it is constant or progressive.

I hope the information will help.

Thanks.

Patient's Query

Hi doctor,

Thank you for the response.

Is the stroke in the midbrain responsible for such brain changes, as the patient has had hypertension for quite several years? Can medication such as brain tonics, thinners, and statins improve the patient's well-being? I read somewhere that a PET scan can give false readings of hypometabolism.

Thanks.

Hi,

Welcome back to icliniq.com.

I understand your concern.

No, such a minor midbrain stroke cannot cause MCI (minimal cognitive impairment) problem. The primary function of blood thinners and statins is to reduce the risk of a second stroke. Meanwhile, risk factor control, screening for and treating other potential underlying causes, such as thyroid dysfunction or vitamin deficiency, or brain activity disorders, such as subtle seizures or encephalopathic conditions, may improve the MCI. If PET (positron emission tomography) confirms amyloid beta accumulation, it can be used to candidate the patient for Lecanemab. The recent stroke of your patient, regarding its size and location, cannot interfere with the PET result.

I hope this information will help.

Thanks.

Patient's Query

Hi doctor,

Thank for the reply.

Hi,

Welcome back to icliniq.com.

I understand your concern.

You are welcome.

Patient's Query

Hi doctor,

Thank you for your answer.

A recent MRI was done, and my father's memory is not much affected, and he is very independent with his activities of daily living; he insists he is okay, and physically, he is well strong and capable of even running incredibly.

There is, however, more quietness in him; however, with me, he is very conversant and is aware of his surroundings and things happening in the world. Sometimes, he gets confused about following certain things, like if you tell him to do something, please help. Could this all be a manifestation of age-related atrophy and depression? Or is it due to some family-related issues or something like that?

MRI Discussion: Global atrophic changes are identified within the brain more bilaterally in the parietotemporal regions. There is no restricted diffusion to suggest acute infarct. No hydrocephalus or midline shift. Sella, CP angles, and craniocervical junction are normal. No intracranial hemorrhage or mass was seen.

After I/V contrast administration, no abnormal meningeal or brain parenchymal enhancement was seen.

Conclusion:

Global atrophic changes within the brain parenchyma predominantly in the parietal and temporal regions.

Thank you.

Hi,

Welcome back to icliniq.com.

I compared this MRI report with the previous one you uploaded in icliniq a year ago.

As the radiologist did not give any comparison with the previous MRI, and because I haven't seen the original images, I cannot tell you if the atrophy has progressed or not.

As I explained to you previously, based on your description of your father's cognitive function, his condition is suggestive of MCI.

Based on your description, he is still in the MCI phase.

Suppose you and your family members feel that his mood has changed significantly, or his motivation to do activities that he previously was eager to do has decreased notably. A medical treatment such as anti-depressant medications might be needed in that case. Neurodegenerative conditions can also manifest depression-like symptoms.

Moreover, to better judge his cognitive ability, a special test is usually done by neurologists in their offices during the appointment.

I do not know if your father's neurologist has done the test. A physician can detect if the condition is stable or progressive by comparing the test scores at two separate appointment times.

As a general recommendation, it would be beneficial if your father takes daily supplements such as vitamin E and Omega 3 capsules.

Thank you.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Seyedaidin Sajedi
Dr. Seyedaidin Sajedi

Neurology

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