HomeAnswersPsychiatrynauseaI have panic attacks and nausea even after taking Valdoxan. Why?

What causes severe anxiety with nausea and panic attacks?

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Answered by

Dr. Ashok Kumar

Medically reviewed by

iCliniq medical review team

Published At March 5, 2019
Reviewed AtSeptember 13, 2023

Patient's Query

Hello doctor,

I have severe anxiety and struggling majorly with nausea, having multiple panic attacks a day and now stuck for leaving home. 10 years ago they tried Zoloft which worsened symptoms. Then went to Mirtazapine 45 mg and that helped for quite many years. Unfortunately, the last 12 months it has gone back to a severe level. This week a GP doctor has changed me to Valdoxan which I am swapping to this week. I have been told to cut Avanza for two days entirely and start 25 mg Valdoxan which I have but having severe panic attacks and nausea. Wondering if there are better options or what to do. I am at a wits' end with nausea.

Answered by Dr. Ashok Kumar

Hi,

Welcome to icliniq.com.

Although Agomelatine (Valdoxan) is a good medication for treatment of anxiety and panic disorders, it is not the best option. Agomelatine is considered a weak agent and possibility of helping in severe anxiety and panic attacks are less when compare to traditional medications such as SSRI and SNRI. Since one of the SSRI was already tried a few years back with negative results (Zoloft), I feel the SNRI should be considered as the next option. Although four medications are available in this category, I feel Desvenlafaxine (Prestiq) should make a better choice. This is one of the potent anti-anxiety medications and the possibility of a positive response is comparatively better when compared to other similar medications. It is true that it may cause nausea for some days (often less than one week) but this is self-limiting and disappears on its own in a few days and rarely lasts for a week. The next option is to try another SSRI which comes with trade name Paxil. It is again one of the preferred medication in severe anxiety and yields earlier results. It is true that every medication have their own side effects and we need to give a deeper thought before starting any medication.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Ashok Kumar
Dr. Ashok Kumar

Geriatrics

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