HomeAnswersSexologypenile disordersI have mycoplasma genitalium. Please help.

My penile discharge shows Mycoplasma genitalium. Will I be infected forever?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Answered by

Dr. Nidhi Jain

Medically reviewed by

iCliniq medical review team

Published At June 22, 2017
Reviewed AtFebruary 13, 2024

Patient's Query

Hello doctor,

I am a 27 year old male, and I had unprotected sex with a woman, four months back. I started having symptoms a couple of months back. The symptoms were penile discharge, it is transparent, and I feel tickling on the penis. This made me take some STI tests, and I was diagnosed with mycoplasma genitalium. PCR was carried out to check for the following STIs, Chlamydia trachomatis, Mycoplasma hominis, Neisseria gonorrhoeae, Trichomonas vaginalis, Treponema pallidum, Ureaplasma urealyticum, Ureaplasma parvum, HSV 1 and 2, proviral HIV DNA, and all results were negative, except Mycoplasma genitalium, which was positive. Additionally, to the above PCR test, I did a blood test as well for VDRL, HBsAg, and anti-HCV, which were also negative.

After visiting my doctor, I started taking two antibiotics, that is, Zithromax, only the first day of the treatment, and then Ciproxin 500 mg for three weeks. At the beginning of last month, I got tested by PCR method again and found positive for Mycoplasma genitalium. The doctor after reviewing the results suggested taking another 2 g Zithromax. After getting the last dose of 1 g Zithromax three weeks later,  I got tested again by PCR method and found positive for Mycoplasma genitalium. On the same day of the test, I got a urine test, which showed 11000 WBC. So, the doctor suggested getting a urine culture, which showed 1000 CFU. Is this something I have to worry about? Will I be infected forever? If I meet my wife in a couple of years, will she be infected because of me? What is the next treatment? I still have penile discharge. This is something that stresses me a lot. Please advise.

Answered by Dr. Nidhi Jain

Hello,

Welcome to icliniq.com.

  • You might be suffering from the resistant strain of Mycoplasma. I would advise you to go for culture and sensitivity test. The sensitivity test would tell us about the mycoplasma sensitive antibiotic.
  • Nevertheless, I suggest trying Doxycycline 100 mg, twice daily for 21 days.

Hope it helps. If you have any other question, please do not hesitate to contact me. Regards.

For more information consult a sexologist online --> https://www.icliniq.com/ask-a-doctor-online/sexologist

Patient's Query

Hello doctor,

Thank you for replying. Is it curable? Is it possible that the infection will not be cured at all? The doctor said Doxycycline is not very effective. Do people live with this infection forever?

Answered by Dr. Nidhi Jain

Hi,

Welcome back to icliniq.com.

  • Yes, it may be, but very rarely it happens.
  • Doxycycline is the drug of choice in Mycoplasma infection. The best antibiotic can only be given after the sensitivity testing.

Hope it helps. If you still have any other question, feel free to ask. Regards.

For further queries consult a sexologist online --> https://www.icliniq.com/ask-a-doctor-online/sexologist

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Nidhi Jain
Dr. Nidhi Jain

Psychiatry

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