HomeAnswersUrologypsa levelWhat causes abnormal free PSA results?

Why is my free PSA abnormal?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

Dr. Divya Banu M

Published At May 5, 2019
Reviewed AtJuly 13, 2023

Patient's Query

Hello doctor,

50 years old, 5.8 inches, 260 lbs. On blood pressure pills. My doctor is out of town for a few weeks. I reviewed PSA test results and apparently I have one abnormal reading out of three. PSA total 0.5, PSA free 0.1, PSA % free 20. The PSA % free 20 is in red indicating abnormal. What does this mean? What causes it to be abnormal?

Hi,

Welcome to icliniq.com.

Free PSA should be more than 15 % to rule out prostate cancer. Free PSA is an additional tool used when PSA is above 2.5 and we want to check whether high PSA is due to benign prostate growth or due to prostate cancer. Some laboratories use 25 % cutoff, but most have 15 % cutoff value. Since your total PSA is quite low and free PSA is above 15 %, you should not worry. If in doubt, repeat after a few months.

Patient's Query

It should mot matter that I have an asymmetric prostate?
No. Unless the doctor feels on rectal examination any nodule or hardness. If so, he may ask for TRUS and TRUS guided biopsies.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Saurabh Subhash Pandya
Dr. Saurabh Subhash Pandya

Urology

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