I am 27. Does Levetiracetam for seizures cause side effects?

Question

Hello doctor,

I am 27 years old and had my first seizure last month. An MRI (magnetic resonance imaging) of the brain was normal, but my EEG (electroencephalogram) showed mild epileptiform activity. The doctor started me on Levetiracetam 500 mg twice daily. Since starting the medication, I have been experiencing mood swings and slight dizziness.

Is this a common side effect, or should I request a dose adjustment?
My vitamin B12 level is 210 pg/mL, and my sodium level was slightly low at 132 mmol/L. Could these be possible triggering factors?
Do I need to continue the medication lifelong, or can seizures completely go away with time?
Are there any specific foods or sleep restrictions I should follow?

Please help.

Thank you.

Answer 1

Hello,

Welcome to icliniq.com.

I have gone through your query and understand your concern.

Levetiracetam is a commonly prescribed and effective medicine for seizure prevention. The mood swings, irritability, and mild dizziness you are experiencing are recognized side effects of this drug, especially in the initial weeks. In many patients, these symptoms improve with time, but if they persist or significantly affect daily life, you should discuss this with your neurologist. Sometimes, a dose adjustment or adding a vitamin B6 supplement can help.

Your vitamin B12 level is low, and low sodium can also lower the seizure threshold. Correcting these deficiencies with supplementation and regular monitoring will support better seizure control.

Regarding the duration of treatment, after a first seizure with EEG (electroencephalogram) changes, anti-seizure medication is usually advised for at least two to three years with regular follow-up. Some patients may be able to taper off medication later if they remain seizure-free and follow-up EEGs are normal. This decision should always be made under specialist guidance.

Lifestyle advice:

Maintain regular sleep and avoid sleep deprivation.
Avoid alcohol, recreational drugs, and excessive caffeine.
Manage stress and stay well hydrated.
No specific food restrictions, but a balanced diet with adequate B12, folate, and electrolytes is essential.
Avoid driving, swimming alone, or operating heavy machinery until cleared by your neurologist.

I hope I have answered your question.

Let me know if I can assist you further.

Thank you.