Dr. Rajesh Kumar Bansari
Medical Gastroenterology
The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.
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Patient's Query
Hello doctor,
My mother is diabetic and hypertensive. She had some joint pain about two months back, for which she took painkillers for about 20 days and Trinerve for vitamin B12 for about a month. Her HbA1c was 7.6%, so her sugar medicines were also changed. Earlier she was taking Glycomet-GP 3/850 and Voglibose 0.3 mg twice a day. Now the doctor has changed it to Glycomet Trio 2 Tablet SR and introduced Gliptagreat 50 twice a day. She has been taking these two sugar medicines for the past three weeks. The past week, she has had some itching in her feet and hands without rashes. The doctor suggested Allegra 120 mg. After taking 4 doses she was better and there was no itching. We did her CBC and LFT and we also did her Vitamin B 12 test. Kindly look into her reports; the liver enzymes are mildly high. Also, please see her attatched ultrsound reports too. Could it be due to the painkillers she had taken? Couldit be due to the new medicine Glipatgreat 50? Is itching related to any ofthese or high B 12 because of supplements? I will also share the report from two months back. She also takes Temisat Am, Alprazolam 0.5 mg, Nexito 10mg, Glycomet GP 3, and Ecospirin 75 mg. Kindly advise.
Hello,
Welcome to icliniq.com
I have read your query and understand your concern.
I have reviewed the reports (attachment removed to protect the patient's identity).
Pain killers affect the stomach causing peptic ulcers rather than the liver, but if painkillers are taken for a longer duration, they may affect the liver in some cases. In this case, it might be due to fatty liver, which is very common in diabetic and overweight patients. So the conditions you have explained might not be due to the new medicines for diabetes. The itching might be due to some allergy, but I cannot say which drug is causing it. If you have started other new medicines, please stop using them after consulting the doctor. Please check for antibodies for HBsAg (hepatitis B surface antigen) and HCV (hepatitis C virus). If both are negative, I suggest you start medication for fatty liver.
Kindly revert back in case of more queries.
Thank you.
Patient's Query
Thank you for your reply doctor,
As she is already taking so many medicines, can we reduce the fatty liver by diet or exercise? Can these liver enzymes be reversed naturally or do we have to take medicines? Kindly guide me.
Hello,
Welcome back to icliniq.com
Reducing the weight through diet and exercise will eventually bring the liver enzymes back to normal. If she can do it, then this is the best way to make herself healthy.
Thank you.
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Medical Gastroenterology
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