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What symptoms can I expect with positive HLA-B27 and spondyloarthritis?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

Dr. Vinodhini J.

Published At August 18, 2020
Reviewed AtJanuary 17, 2024

Patient's Query

Hello doctor,

I am an 18-year-old female. Six months ago, I did some blood tests and my doctor said that I resulted positive for HLA-B27 and that she suspects me to have spondyloarthritis. But she did not explain to me things that I can or cannot do from now on. I take one tablet of vitamin D weekly and anti-inflammatory medication. Can you tell me about people that have the type I have? What should I not do in my daily life and what symptoms should I be curious about? And can I donate blood?

Hi,

Welcome to icliniq.com.

Spondyloarthritis (SpA) is a group of disorders that predominantly affects (inflammation or arthritis) in the spine and lower limbs. The common diseases which come under SpA are ankylosing spondylitis, reactive arthritis, psoriatic arthritis, etc. HLA-B27 is a gene that is found more frequently in the SpA group of diseases. You can do all activities like a normal person. Regular exercise and active life are advised in SpA. Monitor your symptoms like early morning stiffness for more than 30 minutes, arthritis of joints, eye inflammation, pain abdomen and blood in the stool. Yes, you can donate your blood. This is not a blood born disease. So, it will never be transmitted to anyone via blood. You can enjoy your life like an HLA B27-negative person with regular medicines and treatment under the guidance of a Rheumatologist. You should avoid unhealthy foods and weight gain. Knowledge of good posture and back exercise is very important in SpA. I hope this helps.

Thank you.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Rajiv Ranjan Kumar
Dr. Rajiv Ranjan Kumar

Rheumatology

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