HomeAnswersPsychiatryssriWhat medications can be used for chronic GAD and SAD?

Which SSRIs combination medication is the best to treat chronic GAD and SAD and has fewer side effects?

Share

The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

iCliniq medical review team

Published At May 5, 2023
Reviewed AtOctober 11, 2023

Patient's Query

Hello doctor,

My psychiatrist has decided for years to use only a combination of SSRI and Busipirone permanently to control and manage my chronic GAD and SAD. Which among the SSRIs combination is the best and has the fewest side effects?

Kindly help.

Hello,

Welcome to icliniq.com.

Thank you for your query.

I understand your concern. Coming to SSRI first, the side effects such as sedation and weight gain issue is lower with Prozac ( Fluoxetine). While Zoloft (Sertraline) has a lower rate of weight gain and sedation is a little higher compared to Prozac. While Lexapro (Escitalopram) has a little higher incidence of sedation and weight gain. Sexual dysfunctions are more or less equal to all these drugs. All these SSRIs are quite safe for long-term use. Initially, Prozac can cause some anxiety symptoms. So overall you can choose from Prozac or Zoloft and Buspirone considering your side effects profile.

I hope this has helped you. Thank you.

Patient's Query

Hello doctor,

Thank you for your reply but I have just one thing that confused me. How is Prozac less likely to cause weight gain and it is a 5-HT2C antagonist?

Hello,

Welcome back to icliniq.com.

Yes, Prozac can also cause weight gain but the weight gain is less compared to other SSRIs. It is only relative to other SSRIs.

I hope this has helped you. Thank you.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Ramchandra Lamba
Dr. Ramchandra Lamba

Psychiatry

Community Banner Mobile
By subscribing, I agree to iCliniq's Terms & Privacy Policy.

Ask your health query to a doctor online

Psychiatry

*guaranteed answer within 4 hours

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.

This website uses cookies to ensure you get the best experience on our website. iCliniq privacy policy