Thalassemia Major

Thalassemia major is a type and most severe form of beta thalassemia, which is a genetic condition where the body cannot produce globin. It causes severe anemia, which can be life-threatening. The other symptoms are fussiness, pale skin, poor appetite, jaundice, and enlarged organs.

Recently Answered Questions Recently Answered Questions

All the answers published in this website are written by Verified medical doctors, therapists and health experts. The Content has been moderated by iCliniq medical review team before publication. Post your medical clarifications on iCliniq by choosing the right specialty and get them answered. Your medical queries will be answered 24/7 by top doctors from iCliniq.

Can beta-thalassemia minor be treated?

Query: Hi doctor, One of my daughters has got beta thalassemia major and G6PD deficiency. Is there any treatment for her? Please advice.  Read Full »

Dr. Geetha Priyadarsini Kamminana

Answer: Hello, Welcome to Beta thalassemia major includes a hereditary disorder and is due to genetic deficiency of beta globin chains of hemoglobin. It is transfusion dependent anemia.Management of beta thalassemia major includesChronic transfusion to maintain hemoglobin at the range of 9-10 ...  Read Full »

What causes headache in a child with thalassemia major?

Query: Hi doctor, My son is thalassemia major subject. His age is 6 months(male boy). His weight is 5. He is suffering from headache and fever every now and then. Some times heart beet is fast. His liver and spleen are enlarged. He has been blood transfusion in one time in last week. Now he is taking foli...  Read Full »

Dr. Preeti Puranik

Answer: Hi, Welcome to He is suffering from thalassemia major. Here there is destruction of the blood cells due to which haemoglobin becomes low frequently. Hence he will need blood transfusions regularly. He is prone for infections because of low haemoglobin which can also cause fast heartbe...  Read Full »

What is the suggested food for a baby with thalassemia major?

Query: Hello doctor, My baby girl is 3.5 years old. She has thalassemia major and her ferritin level is 3000 ng/ml. What food is good for her?  Read Full »

Dr. Prakash H. Muddegowda

Answer: Hello, Welcome to Based on your query, my opinion is as follows: Iron intake should be reduced. Vegetarian diet will be better as iron content is low. The diet that can be followed include: 1. Importantly avoid vitamin C or citrus food up to four hours after food as it helps in impr...  Read Full »

Please suggest a diet chart for thalassemia patient.

Query: Hi doctor, My brother is a thalassemia major subject. His age is 18 years and height is 5'4''. His hemoglobin is always maintained between 9 and 10 units. His weight is 38 now and drastically reducing. Nowadays he has been having headache and fever now and then. Sometimes he feels that his heartbeat...  Read Full »

Dr. Prakash H. Muddegowda

Answer: Hi, Welcome to Based on your query regarding thalassemia, my opinion is as follows:1. Looking at a regular hemoglobin level of 9-10%, I would suggest you increase the levels. Maintaining at this level increases further erythropoiesis (production of red blood cells). Close to 12-13 g% ...  Read Full »

My 5-year-old daughter has beta-thalassemia major with enlarged spleen. Will she be transfusion dependent?

Query: Hello doctor,I am a beta thalassemia minor, but my wife is not. Recently my 5-year daughter was diagnosed with beta-thalassemia major (heterozygous). She is active and playful. No problem reported yet, but her Hb level is between 7.8 to 8.8 from starting. Her spleen is enlarged as diagnosed in USG. ...  Read Full »

Dr. Parth R Goswami

Answer: Hello, Welcome to the If you are having thalassemia minor and your wife is thalassemia negative than there is no chance of acquiring thalassemia major in your child.So your wife must also have thalassemia minor if your child is thalassemia major. Your child's attached report suggestiv...  Read Full »

Please suggest treatment for thalassemia major.

Query: Hi doctor, I am a thalassemia major patient. My spleen size is 21. How to reduce my spleen size? And also I want to increase my weight? My age is 21. How much percentage risk is present in the unrelated donor stem cell transplant? My ferritin is 1500 and weight is 48 kg. Please suggest some solution...  Read Full »

Dr. Sumit Srivastava

Answer: Hi, Welcome to At present there is no way to reduce the spleen size. Diet for thalassemia major patient should include plenty of fruits and vegetables and protein rich diet. Taking vitamin C supplements will help to increase the immunity of the body. Bone marrow transplantation is a...  Read Full »

Thalassemia major with factor 13 deficiency and high ferritin levels. Please advise.

Query: Hello doctor, I am thalassemia major with factor XIII decficiency, HCV+. I transfuse platelet or FFp daily and RCC weekly. All these things are reacting in my body. My ferritin level is 15000 after chelation therapy. This also reacts badly every time. I am 28 years old. How much time do I have to l...  Read Full »

Dr. Prakash H. Muddegowda

Answer: Hi, Welcome to Based on your query, my opinion is as follows: The serum ferritin level of 15000 is definitely too high. Along with HCV, the prognosis is somewhat poor. However, without knowing the amount of iron deposition in tissues like the liver, heart, etc, and also the amount o...  Read Full »

How can excess iron be removed from heart and liver in a thalessemia patient?

Query: Hello doctor, My brother is a Thalassemia major patient. He goes through regular bi-weekly blood transfusions. He has been also taking one Desferal injection on daily basis. Recently T2 MRI scan was done for him which shows a severe amount of iron in heart and liver. I need your expert advice on ch...  Read Full »

Dr. Parth R Goswami

Answer: Hello, Welcome to Sorry to hear about your brother condition. To treat chronic iron overload in the body due to thalassemia major, he can be given an intravenous injection or subcutaneous infusion of Desferal. Usually, in such case, 1 to 2 gm daily dose of Desferal might be needed. Th...  Read Full »

What diet will you recommend for a beta major thalassemia patient?

Query: Hi doctor, My daughter, who is 2.5 years old, is suffering from beta major thalassemia. From her 3 months of age, blood has been transfused either once in 30 or 45 days after checking the blood level. I would request you to kindly advise a good and healthy food diet. Is there any important daily die...  Read Full »

Dr. Prakash H. Muddegowda

Answer: Hi, Welcome to Based on your query, my opinion is as follows: Thalassemia is a disease due to reduced globin production in the hemoglobin part of RBC (red blood cells). It is not due to nutritional deficiency, but due to inherited mutation abnormalities. Yes, nutrition requires improvem...  Read Full »

Mine and my wife's blood group is B. Will it cause any problem in our married life?

Query: Hello doctor, My wife's and mine blood groups are the same. Both of our blood group is B. Will there be any problem in our married life?  Read Full »

Dr. Parth R Goswami

Answer: Hi, Welcome to There are two major blood group systems. ABO - According to this system, the blood group can be A, B, O, AB.  Rh system - According to this system, the blood group can be Rh positive or negative. You have not mentioned th...  Read Full »

ask-doctor-img Ask a Doctor Online

* Your first query consult is free!

Search for a Health Issue

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.