Thalassemia Major

Thalassemia major is a type and most severe form of beta thalassemia, which is a genetic condition where the body cannot produce globin. It causes severe anemia, which can be life-threatening. The other symptoms are fussiness, pale skin, poor appetite, jaundice, and enlarged organs.

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I am a thalassemia major patient with HCV. How long can I live?

Query: Hello doctor,I am a thalassemia major with factor XIII deficiency, HCV+. I transfuse platelet or FFP daily and RCC weekly. All these things are reacting in my body. My ferritin level is 15000 after chelation therapy. This also reacts badly every time. I am 28 years old. How much time do I have to li...  Read Full »

Dr. Prakash H. M

Answer: Hi, Welcome to Based on your query, my opinion is as follows: The serum ferritin level of 15000 is too high. Along with HCV, the prognosis is somewhat poor. However, without knowing the amount of iron deposition in tissues like the liver, heart, etc, and also the amount of damage to the...  Read Full »

Please suggest a diet chart for thalassemia patient.

Query: Hi doctor, My brother is a thalassemia major subject. His age is 18 years and height is 5'4''. His hemoglobin is always maintained between 9 and 10 units. His weight is 38 now and drastically reducing. Nowadays he has been having headache and fever now and then. Sometimes he feels that his heartbeat...  Read Full »

Dr. Prakash H. M

Answer: Hi, Welcome to Based on your query regarding thalassemia, my opinion is as follows:1. Looking at a regular hemoglobin level of 9-10%, I would suggest you increase the levels. Maintaining at this level increases further erythropoiesis (production of red blood cells). Close to 12-13 g% ma...  Read Full »

Can beta-thalassemia minor be treated?

Query: Hi doctor, One of my daughters has got beta thalassemia major and G6PD deficiency. Is there any treatment for her? Please advice.  Read Full »

Dr. Geetha Priyadarsini Kamminana

Answer: Hello, Welcome to Beta thalassemia major includes a hereditary disorder and is due to genetic deficiency of beta globin chains of hemoglobin. It is transfusion dependent anemia. Management of beta thalassemia major includes Chronic transfusion to maintain hemoglobin at the range of...  Read Full »

For thalassemia major, when would my son require his first blood transfusion?

Query: Hello doctor, My son is 15 months old and has been diagnosed with thalassemia major. My only question is when he would require his first blood transfusion? Because typically people feel strong symptoms of anemia and need medical help when Hb goes below 6. But, my child has Hb of 3.7 probably for ove...  Read Full »

Dr. Deepak Patel

Answer: Hi, Welcome to I can understand your concerns. The definite management of thalassemia is bone marrow transplant. For this HLA - human leukocyte antigen) matching is done and if possible this is the best treatment available right now. The second one is a regular blood transfusion...  Read Full »

Which is the best diet for someone with thalassemia major?

Query: Hi doctor, I am a patient of thalassemia major. My first blood transfusion was four months ago. There was no need for blood transfusion before that. I have no idea about my disease and now my blood transfusion has reached a count of eight times, meaning eight units in the last three months. I checke...  Read Full »

Dr. Singh Smrita

Answer: Hello, Welcome to In thalassemia major, there is a defect in the production of normal hemoglobin. This affects the oxygen-carrying capacity of the hemoglobin since it is defective. Regular blood transfusions and iron chelation therapy to prevent iron overload is the main treatment. Yo...  Read Full »

What is the suggested food for a baby with thalassemia major?

Query: Hello doctor, My baby girl is 3.5 years old. She has thalassemia major and her ferritin level is 3000 ng/ml. What food is good for her?  Read Full »

Dr. Prakash H. M

Answer: Hello, Welcome to Based on your query, my opinion is as follows: Iron intake should be reduced. Vegetarian diet will be better as iron content is low. The diet that can be followed include: 1. Importantly avoid vitamin C or citrus food up to four hours after food as it helps in impr...  Read Full »

My sister is a thalassemia major patient. What medicines does she need to improve her hemoglobin levels?

Query: Hello doctor, My sister is a thalassemia major (intermediate) patient. Last week she had a fever and dizziness. Also, she gets tired very quickly. Her blood test was done nine months back, and her hemoglobin was 7.2 g/dL. She is currently taking only folic acid, as suggested by her doctor. Does she...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to I understand your concern. Thalassemia major and thalassemia intermediate are two different conditions. A regular blood transfusion is needed in thalassemia major, while in thalassemia intermediate, a blood transfusion might not be required. Iron tablets can be ...  Read Full »

What causes headache in a child with thalassemia major?

Query: Hi doctor, My son is thalassemia major subject. His age is 6 months(male boy). His weight is 5. He is suffering from headache and fever every now and then. Some times heart beet is fast. His liver and spleen are enlarged. He has been blood transfusion in one time in last week. Now he is taking foli...  Read Full »

Dr. Preeti Puranik

Answer: Hi, Welcome to He is suffering from thalassemia major. Here there is destruction of the blood cells due to which haemoglobin becomes low frequently. Hence he will need blood transfusions regularly. He is prone for infections because of low haemoglobin which can also cause fast heartbe...  Read Full »

My 5-year-old daughter has beta-thalassemia major with enlarged spleen. Will she be transfusion dependent?

Query: Hello doctor,I am a beta thalassemia minor, but my wife is not. Recently my 5-year daughter was diagnosed with beta-thalassemia major (heterozygous). She is active and playful. No problem reported yet, but her Hb level is between 7.8 to 8.8 from starting. Her spleen is enlarged as diagnosed in USG. ...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to the If you are having thalassemia minor and your wife is thalassemia negative than there is no chance of acquiring thalassemia major in your child.So your wife must also have thalassemia minor if your child is thalassemia major. Your child's attached report suggestive ...  Read Full »

Please suggest treatment for thalassemia major.

Query: Hi doctor, I am a thalassemia major patient. My spleen size is 21. How to reduce my spleen size? And also I want to increase my weight? My age is 21. How much percentage risk is present in the unrelated donor stem cell transplant? My ferritin is 1500 and weight is 48 kg. Please suggest some solution...  Read Full »

Dr. Srivastava, Sumit

Answer: Hi, Welcome to At present there is no way to reduce the spleen size. Diet for thalassemia major patient should include plenty of fruits and vegetables and protein rich diet. Taking vitamin C supplements will help to increase the immunity of the body. Bone marrow transplantation is a...  Read Full »

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