Q. What should be done when TSH level is 4. 87 at 31st week of pregnancy?

Answered by
Dr. Shaikh Sadaf
and medically reviewed by Nithila A
Published on Sep 15, 2019 and last reviewed on: Sep 19, 2019

Hello doctor,

My wife is at her 31st week of pregnancy, but now her TSH level is 4.87. She is continuing Thyrox 125. What to do?

Dr. Shaikh Sadaf

Diabetology Endocrinology


Welcome to icliniq.com.

I read your query, and from what you have mentioned, it appears that your wife needs to increase the dose of thyroxine to 150 mcg and repeat her thyroid function test after four weeks again. You must repeat her thyroid function test every four weeks during pregnancy. You did not mention what was her dose before getting pregnant? Was this test done while she was fasting? If not then do it again now while she is fasting.

How long does she have hypothyroidism? Is she taking it on empty stomach first thing in the morning and avoiding eating breakfast for the next hour after medication. Secondly, is she taking any iron or calcium supplements together with the thyroid medication as it can interfere with the absorption of thyroid medication? The spacing of any iron or calcium supplements should be at least four hours away from thyroid medication. If she has any problem, she must follow in an emergency or her gynecologist as soon as possible to be on the safe side. I hope you find my advice beneficial.

Thank you doctor,

My wife has twin pregnancy hemoglobin level is 10, the TSH test was done in fasting. So as per your advice, we try Thyrox 150 from tomorrow.

Dr. Shaikh Sadaf

Diabetology Endocrinology


Welcome back to icliniq.com.

Yes, please also repeat the thyroid test after four weeks again.

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