I have been experiencing several side effects such as muscle stiffness, facial twitches, and bad anxiety after taking Ziprasidone. How should I proceed?

Q. How to overcome the side effects caused by tablet Ziprasidone?

Answered by
Dr. Vishal Anilkumar Gandhi
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Apr 08, 2023

Hi doctor,

I am currently taking Ziprasidone for DID and for Bipolar disorder. For the last six months, I have been experiencing several physical side effects such as muscle stiffness, facial twitches, and bad anxiety. It went worse, so that I chose to stop the medication and I was off for three weeks. Then, I had withdrawal side effects like losing track of time or dissociation and overall paranoia. However, since being on Ziprasidone again for four days my side effects are back and I do not know what to do. I do not know if I should quit it once and for all without ever going back or just keep taking it. I just do not know what to do.

#

Hi,

Welcome to icliniq.com.

Thank you for taking help from a psychiatrist.

I can understand your situation. You must continue your Ziprasidone and add a tablet of Pacitane (Trihexyphenidyl) 2 mg daily in the morning. It will subside your Ziprasidone side effects. You have antipsychotic-induced extrapyramidal symptoms (EPS).

So, it will subside by adding the above medication.

I hope that you get your answer.

Please let me know if you want some help.

Thank you.


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