Hi, Welcome to icliniq.com. The median incubation period (interval between contracting infection and clinical manifestations) of primary syphilis is 21 days (ranges from 10 to 90 days), and it rarely exceeds six weeks. Once the primary sore appears, it persists for four to six weeks, and then it heals. Usually, six to eight weeks after healing of primary sore, secondary syphilis becomes clinically apparent. Patient experiences skin rash at this stage.
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