Hi, Welcome to icliniq.com. Ongoing through the report (attachments removed to protect the patient's identity), the probable diagnosis is Stage III cancer (involving left parametrium, left adnexa, and left pelvic lymph nodes). For women requiring first-line chemotherapy for EOC (epithelial ovarian cancer), the standard IV (intravenous) regimen utilizes Platinum and Taxane agents. We prefer Carboplatin rather than Cisplatin because multiple trials have consistently demonstrated that Carboplatin produces equivalent response rates and survival outcomes to Cisplatin but is associated with less toxicity. Although both Paclitaxel and Docetaxel (the most commonly used taxanes for EOC) can be administered along with Carboplatin in this setting, we prefer Paclitaxel because it is less myelosuppressive than Docetaxel.
Hi, Welcome to icliniq.com. May I examine the lesion for better diagnosis and treatment, which includes many differential diagnoses? White or red oral lesions include benign lesions (e.g., morsicatio buccarum and frictional keratosis, white sponge nevus [WSN]), benign lesions with malignant potential (e.g.
Hi, Welcome to icliniq.com. In reply to your question for Osimertinib (Tagrisso), Osimertinib demonstrated improvement in PFS (18.9 versus 10.2 months, HR 0.46, 95% CI 0.
Hi, Welcome to icliniq.com. I have gone through the picture and blood investigations that you sent. (attachment removed to protect patient identity). This lesion is asymmetric and presents irregular borders and irregular distribution of the pigmentation presents border irregularity, color variation, and a nodular component of diameter ≥6 mm. Before I make further diagnosis, I would like to know for the last few months is there any change in size and new lesion? Change in color? Change in shape? Is there inflammation? Bleeding or crusting? Sensory change? Lesion diameter ≥7 mm? Meanwhile, I would like to classify this lesion as suspicious and would like to advise biopsy.
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