"Alpha thalassemia refers to an inherited blood disorder that causes a reduction in hemoglobulin production. It typically occurs due to the deletion of the HBA1 and HBA2 genes. These two genes provide instructions to make a protein called alpha-globin, a component of hemoglobulin. There are four types of alpha thalassemia- alpha thalassemia silent carrier, alpha thalassemia carrier, Hemoglobulin H disease, and alpha thalassemia major. People with thalassemia have anemia, weakness, fatigue, enlarged liver or spleen, yellowish skin, and leg ulcers. Treatment of thalassemia may include daily doses of folic acid, blood transfusions, surgery to remove the spleen, and iron chelation therapy. "
Alpha Thalassemia - Types, Risk Factors, Symptoms, Diagnosis, and Management
Alpha thalassemia is a spectrum of genetic disorders that affect the proper functioning of red blood cells. This article reviews alpha thalassemia in detail.