Bedaquiline is an antibiotic used for the treatment of drug-resistant tuberculosis (TB). It works by inhibiting the ATP synthase enzyme of mycobacteria, which is essential for their survival. Bedaquiline is usually administered orally as part of combination therapy for MDR-TB(Multidrug-resistant tuberculosis), and it has been shown to improve treatment outcomes and reduce mortality rates. However, it is not recommended as a first-line treatment due to the risk of developing drug-resistant strains of TB.
Bedaquiline - Indications, Doses, Toxicities, and Mechanism of Action
Bedaquiline is a novel anti-tuberculosis drug used to treat multidrug-resistant tuberculosis (MDR-TB).
